Compound
monodehydro-L-ascorbate radical
The conjugate base of monodehydro-L-ascorbic acid arising from deprotonation of the 4-hydroxy group; major species at pH 7.3.
Definition from ChEBI (CHEBI:59513), read 2026-09-23. CC BY 4.0.
Structure
No three-dimensional record for this entry.
- Class
- Organic compound, anion
- Formula
- C6H6O6
- Mass
- 174.108 g/mol
- Charge
- -1
- InChIKey
- LHFJOBMTAJJOTB-JLAZNSOCSA-M
- SMILES
- [H][C@]1([C@@H](O)CO)OC(=O)C([O-])=C1[O]
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
4 entities
4 entities reached.
0 reported hops4 assembled from the scaffold
- CYBRD1ProteinUNIPROT:Q53TN4substrate of, transported byInferred only84 paths84 endpoints
- PAMProteinUNIPROT:P19021substrate ofInferred only70 paths10 endpoints
- L-ascorbic acidCompoundCHEBI:29073converted toInferred only39 paths12 endpoints
- CYB561ProteinUNIPROT:P49447transported byInferred only33 paths33 endpoints
What the reference databases state
Statements
20 statements
20 statements · 2 reference databases · Subject: monodehydro-L-ascorbate radical · Sources: Human-GEM, Rhea
- monodehydro-L-ascorbate radical is converted to dehydroascorbic acidCompoundHuman-GEM MAR03265Inferred only
- monodehydro-L-ascorbate radical is converted to dehydroascorbic acidCompoundHuman-GEM MAR06393Inferred only
- monodehydro-L-ascorbate radical is converted to L-ascorbic acidCompoundRhea RHEA:30263Inferred only
- monodehydro-L-ascorbate radical is converted to L-ascorbic acidCompoundRhea RHEA:30243Inferred only
- monodehydro-L-ascorbate radical is converted to L-ascorbic acidCompoundRhea RHEA:14581Inferred only
- L-ascorbic acid is converted to monodehydro-L-ascorbate radicalCompoundRhea RHEA:14581Inferred only
- L-ascorbic acid is converted to monodehydro-L-ascorbate radicalCompoundRhea RHEA:30243Inferred only
- L-ascorbic acid is converted to monodehydro-L-ascorbate radicalCompoundRhea RHEA:30263Inferred only
- monodehydro-L-ascorbate radical is a substrate of CYBRD1ProteinRhea RHEA:66656Inferred only
- monodehydro-L-ascorbate radical is a substrate of PAMProteinRhea RHEA:58600Inferred only
- monodehydro-L-ascorbate radical is a substrate of PAMProteinRhea RHEA:58608Inferred only
- monodehydro-L-ascorbate radical is a substrate of PAMProteinRhea RHEA:58612Inferred only
Show the remaining 8
- monodehydro-L-ascorbate radical is a substrate of PAMProteinRhea RHEA:21452Inferred only
- monodehydro-L-ascorbate radical is a substrate of PAMProteinRhea RHEA:58540Inferred only
- monodehydro-L-ascorbate radical is a substrate of PAMProteinRhea RHEA:58544Inferred only
- monodehydro-L-ascorbate radical is a substrate of PAMProteinRhea RHEA:58548Inferred only
- monodehydro-L-ascorbate radical is transported by CYB561ProteinRhea RHEA:66524Inferred only
- monodehydro-L-ascorbate radical is transported by CYB561D1ProteinRhea RHEA:66524Inferred only
- monodehydro-L-ascorbate radical is transported by CYB561D2ProteinRhea RHEA:66524Inferred only
- monodehydro-L-ascorbate radical is transported by CYBRD1ProteinRhea RHEA:66524Inferred only
Reactions
26 reactions
8-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoate+CHEBI:17208+dioxygenMAM01063c+monodehydro-L-ascorbate radical
Reaction pageLeft to rightBalancedcytosol
Human-GEM MAR01356CC BY 4.0Reference data
MAM01246c+CHEBI:17208+dioxygenMAM01223c+monodehydro-L-ascorbate radical
Reaction pageLeft to rightBalancedcytosol
Human-GEM MAR01359CC BY 4.0Reference data
MAM00302c+CHEBI:17208+dioxygenMAM01222c+monodehydro-L-ascorbate radical
Reaction pageLeft to rightBalancedcytosol
Human-GEM MAR01362CC BY 4.0Reference data
MAM00335c+CHEBI:17208+dioxygenMAM00281c+monodehydro-L-ascorbate radical
Reaction pageLeft to rightBalancedcytosol
Human-GEM MAR01365CC BY 4.0Reference data
MAM00275c+CHEBI:17208+dioxygenMAM00368c+monodehydro-L-ascorbate radical
Reaction pageLeft to rightBalancedcytosol
Human-GEM MAR01415CC BY 4.0Reference data
MAM00312c+monodehydro-L-ascorbate radicalMAM00313c+CHEBI:17208+dioxygen
Reaction pageReversibleBalancedcytosol
Human-GEM MAR02446CC BY 4.0Reference data
monodehydro-L-ascorbate radicaldehydroascorbic acid+proton
Reaction pageLeft to rightUnbalancedEC 1.1.1.188cytosol
Human-GEM MAR03265CC BY 4.0Reference data
water+monodehydro-L-ascorbate radicaldehydroascorbic acid+water
Reaction pageLeft to rightUnbalancedcytosol
Human-GEM MAR06393CC BY 4.0Reference data
MAM01330c+monodehydro-L-ascorbate radicalMAM01331c+CHEBI:17208
Reaction pageReversibleBalancedcytosol
Human-GEM MAR06423CC BY 4.0Reference data
CHEBI:17208+MAM03119cmonodehydro-L-ascorbate radical+urate
Reaction pageReversibleBalancedcytosol
Human-GEM MAR06606CC BY 4.0Reference data
2monodehydro-L-ascorbate radical+NADH(2-)+hydron2L-ascorbic acid+NAD(1-)
Reaction pageDirection not assertedBalanced
Rhea RHEA:14581CC BY 4.0Reference data
dopamine+2L-ascorbic acid+dioxygen(R)-noradrenaline+2monodehydro-L-ascorbate radical+water
Catalysed by DBH
Reaction pageLeft to rightBalanced
Rhea RHEA:19117CC BY 4.0Reference data
Where it reaches
10 systems, 24 regions, 106 tissues, 112 transporter routes — routes, not measurements: transporters known to carry monodehydro-L-ascorbate radical are expressed there, and no source reports it arriving.
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Other names
2 names
Resolves to: monodehydro-L-ascorbate radical
- Also called
- monodehydroascorbate anion
- Systematic name
- [(2R)-2-(1,2-dihydroxyethyl)-4-oxido-5-oxo-2,5-dihydrofuran-3-yl]oxidanyl