Compound

chondroitin sulfate

Any of a class of 10—60 kDa glycosaminoglycan sulfates, widely distributed in cartilage and other mammalian connective tissues.

CHEBI:37397ChEBI

Studied for

1 endpoint, 1 finding, from 1 paper.

Radiographic joint-space narrowinglowersGrade D, Preliminary. Non-human or in vitro only.

Every finding, with the quotes

What the evidence says

How to read these marks

1 finding across 1 endpoint, from 1 paper, strongest first.

Heavier lines are better evidence, and a line with a gap in the middle is an inference rather than a reported result. Two lines arriving at one endpoint are two findings of it, marked ×2. How a grade is computed.

What moved

1 finding

Decreases radiographic joint-space narrowing
PreliminaryGrade D, Preliminary. Non-human or in vitro only.Finding
“These results demonstrate that chondroitin sulfate is effective for reducing the rate of decline in minimum joint space width in patients with OA of the knee.”
Quoted verbatim from The rate of decline of joint space width in patients with osteoarthritis of the knee: a systematic review and meta-analysis of randomized placebo-controlled trials of chondroitin sulfate ..
Study

meta-analysis
Population

patients with OA of the knee
The rate of decline of joint space width in patients with osteoarthritis of the knee: a systematic review and meta-analysis of randomized placebo-controlled trials of chondroitin sulfate .2008PMID:18826751