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Catalyst

chondroitin sulfateFinding

Chondroitin sulfate decreases WOMAC pain subscale

lowersModerate evidenceFinding

01 · The sentence it was drawn from

“Similar patterns were observed for the K-WOMAC subscale scores: the reductions from baseline in pain, stiffness, and physical function were significantly greater in the CS group than in the placebo group at both week 6 and week 12 (all p < 0.001).”
Quoted verbatim from Effects of Chondroitin Sulfate on Joint Symptoms and Physical Function in Adults with Mild Knee Osteoarthritis: A Randomized, Double-Blind, Placebo-Controlled Trial.
This finding among the 5 findings on its endpoint

chondroitin sulfate

WOMAC pain subscale

lowers

Who
Adults aged 45-74 years with mild (Kellgren-Lawrence grade II) knee osteoarthritis; Korean version of WOMAC, pain subscale scored 0-20 on a 5-point item scale; change from baseline
Dose studied
1200 mg/day (two 600 mg tablets once daily) of chondroitin sulfate sodium, bovine cartilage origin

Moderate evidencePMID 42942962 · 2026

02 · The study

Study
RCT
Duration
3 months

Evidence, by strength

  • strong
  • moderatethis finding
  • limited
  • very limited
  • insufficient

03 · The paper

Nutrients
What else it reported3 findings · 1 compound · 3 endpoints

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M6ZDJQTTJP5N5VVJNTD6G074