PapersPMID:42942962
Effects of Chondroitin Sulfate on Joint Symptoms and Physical Function in Adults with Mild Knee Osteoarthritis: A Randomized, Double-Blind, Placebo-Controlled Trial.
- findings
- 3
- compound
- 1
- endpoints
- 3
- Study, every finding
- RCT · 3 months
- Dose studied, every finding
- 1200 mg/day (two 600 mg tablets once daily) of chondroitin sulfate sodium, bovine cartilage origin
What moved
How to read these marks →“Similar patterns were observed for the K-WOMAC subscale scores: the reductions from baseline in pain, stiffness, and physical function were significantly greater in the CS group than in the placebo group at both week 6 and week 12 (all p < 0.001).”
- Decreases WOMAC pain subscale
moderate
- Interests
- Industry funded
- Population
- Adults aged 45-74 years with mild (Kellgren-Lawrence grade II) knee osteoarthritis; Korean version of WOMAC, pain subscale scored 0-20 on a 5-point item scale; change from baseline
- Interests
- Industry funded
- Population
- Adults aged 45-74 years with mild (Kellgren-Lawrence grade II) knee osteoarthritis; Korean version of WOMAC, stiffness subscale scored 0-8 on a 5-point item scale; change from baseline
- Interests
- Industry funded
- Population
- Adults aged 45-74 years with mild (Kellgren-Lawrence grade II) knee osteoarthritis; Korean version of WOMAC, physical function subscale scored 0-68 on a 5-point item scale; change from baseline
Study record
- Design
- randomised controlled trial
- Species
- human
- Population
- Adults aged 45 to 74 years with mild knee osteoarthritis (Kellgren-Lawrence grade II) recruited at one Korean medicine hospital; bovine-cartilage chondroitin sulfate sodium, 1200 mg/day
- Participants
- 100
- Comparator
- placebo
- Duration
- 84 days
- Endpoints measured
- 36