Compound
7,8-dihydroneopterin 3'-triphosphate
Tetraanion of 7,8-dihydroneopterin 3'-triphosphate.
Definition from ChEBI (CHEBI:58462), read 2026-09-23. CC BY 4.0.
Structure
No depiction stored
Loading the model…
- Class
- Organic compound, anion
- Formula
- C9H12N5O13P3
- Mass
- 491.139 g/mol
- Charge
- -4
- InChIKey
- DGGUVLXVLHAAGT-XINAWCOVSA-J
- SMILES
- Nc1nc2c(c(=O)n1)N=C([C@H](O)[C@H](O)COP(=O)([O-])OP(=O)([O-])OP(=O)([O-])[O-])CN2
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
6 entities
6 entities reached.
0 reported hops6 assembled from the scaffold
- GCH1ProteinUNIPROT:P30793substrate ofInferred only60 paths20 endpoints
- ALPLProteinUNIPROT:P05186substrate ofInferred only30 paths15 endpoints
- PTSProteinUNIPROT:Q03393substrate ofInferred only22 paths11 endpoints
- ALPIProteinUNIPROT:P09923substrate ofInferred only15 paths15 endpoints
- ALPPProteinUNIPROT:P05187substrate ofInferred only8 paths8 endpoints
- ALPGProteinUNIPROT:P10696substrate ofInferred only5 paths5 endpoints
What the reference databases state
Statements
13 statements
13 statements · 2 reference databases · Subject: 7,8-dihydroneopterin 3'-triphosphate · Sources: Human-GEM, Rhea
- 7,8-dihydroneopterin is converted to 7,8-dihydroneopterin 3'-triphosphateCompoundHuman-GEM MAR02186Inferred only
- 7,8-dihydroneopterin 3'-triphosphate is converted to 7,8-dihydroneopterinCompoundHuman-GEM MAR02186Inferred only
- 7,8-dihydroneopterin 3'-triphosphate is converted to 7,8-dihydroneopterinCompoundHuman-GEM MAR04816Inferred only
- 7,8-dihydroneopterin 3'-triphosphate is a substrate of ALPGProteinHuman-GEM MAR04816Inferred only
- 7,8-dihydroneopterin 3'-triphosphate is a substrate of ALPIProteinHuman-GEM MAR04816Inferred only
- 7,8-dihydroneopterin 3'-triphosphate is a substrate of ALPLProteinHuman-GEM MAR02186Inferred only
- 7,8-dihydroneopterin 3'-triphosphate is a substrate of ALPLProteinHuman-GEM MAR04816Inferred only
- 7,8-dihydroneopterin 3'-triphosphate is a substrate of ALPPProteinHuman-GEM MAR04816Inferred only
- 7,8-dihydroneopterin 3'-triphosphate is a substrate of GCH1ProteinHuman-GEM MAR04817Inferred only
- 7,8-dihydroneopterin 3'-triphosphate is a substrate of GCH1ProteinHuman-GEM MAR04818Inferred only
- 7,8-dihydroneopterin 3'-triphosphate is a substrate of GCH1ProteinRhea RHEA:17473Inferred only
- 7,8-dihydroneopterin 3'-triphosphate is a substrate of PTSProteinHuman-GEM MAR04163Inferred only
Show the remaining 1
- 7,8-dihydroneopterin 3'-triphosphate is a substrate of PTSProteinRhea RHEA:22048Inferred only
Reactions
15 reactions
7,8-dihydroneopterin 3'-triphosphate
Reaction pageReversibleBalance undeterminableextracellular space
Human-GEM MAR01871CC BY 4.0Reference data
7,8-dihydroneopterin 3'-triphosphate+3water7,8-dihydroneopterin+2proton+3phosphate(3-)
Catalysed by ALPL
Reaction pageReversibleBalancedEC 3.1.3.1extracellular space
Human-GEM MAR02186CC BY 4.0Reference data
GTP+water7,8-dihydroneopterin 3'-triphosphate+formic acid+proton
Catalysed by GCH1
Reaction pageLeft to rightBalancedEC 3.5.4.16cytosol
Human-GEM MAR04160CC BY 4.0Reference data
GTP+water7,8-dihydroneopterin 3'-triphosphate+formic acid+proton
Catalysed by GCH1
Reaction pageLeft to rightBalancedEC 3.5.4.16nucleus
Human-GEM MAR04162CC BY 4.0Reference data
7,8-dihydroneopterin 3'-triphosphateMAM01170c+triphosphate
Catalysed by PTS
Reaction pageLeft to rightBalancedEC 4.2.3.12cytosol
Human-GEM MAR04163CC BY 4.0Reference data
7,8-dihydroneopterin 3'-triphosphate+3water7,8-dihydroneopterin+2proton+3phosphate(3-)
Catalysed by ALPL or ALPP or ALPG or ALPI
Reaction pageLeft to rightBalancedEC 3.1.3.1cytosol
Human-GEM MAR04816CC BY 4.0Reference data
MAM00574c7,8-dihydroneopterin 3'-triphosphate+water
Catalysed by GCH1
Reaction pageReversibleBalancedEC 3.5.4.16cytosol
Human-GEM MAR04817CC BY 4.0Reference data
MAM00574n7,8-dihydroneopterin 3'-triphosphate+water
Catalysed by GCH1
Reaction pageReversibleBalancedEC 3.5.4.16nucleus
Human-GEM MAR04818CC BY 4.0Reference data
7,8-dihydroneopterin 3'-triphosphateMAM01170n+triphosphate
Reaction pageLeft to rightBalancedEC 4.2.3.12nucleus
Human-GEM MAR08738CC BY 4.0Reference data
GTP+water7,8-dihydroneopterin 3'-triphosphate+formate+hydron
Catalysed by GCH1
Reaction pageDirection not assertedBalanced
Rhea RHEA:17473CC BY 4.0Reference data
7,8-dihydroneopterin 3'-triphosphate6-pyruvoyl-5,6,7,8-tetrahydropterin+triphosphate+hydron
Catalysed by PTS
Reaction pageDirection not assertedBalanced
Rhea RHEA:22048CC BY 4.0Reference data
7,8-dihydroneopterin 3'-triphosphate+waterCHEBI:58762+diphosphate(3-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:25302CC BY 4.0Reference data
Other names
2 names
Resolves to: 7,8-dihydroneopterin 3'-triphosphate
- Also called
- 7,8-dihydroneopterin 3'-triphosphate tetraanion
- Systematic name
- (2R,3S)-3-(2-amino-4-oxo-3,4,7,8-tetrahydropteridin-6-yl)-2,3-dihydroxypropyl triphosphate