Compound

15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate

A polyunsaturated oxo fatty acid anion that is the conjugate base of 15-oxo-ETE.

Definition from ChEBI (CHEBI:57410), read 2026-09-23. CC BY 4.0.

CHEBI:57410ChEBI

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Structure

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A generated conformer of 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate — one low-energy arrangement PubChem computed, not a measured structure. Hydrogens are not drawn; the formula counts them.

Class: Organic compound, anion
Formula: C20H29O3
Mass: 317.449 g/mol
Charge: -1
InChIKey: YGJTUEISKATQSM-USWFWKISSA-M
SMILES: CCCCCC(=O)/C=C/C=CC/C=CC/C=CCCCC(=O)[O-]
Look it up: ChEBI PubChem By InChIKey

Identity from ChEBI, geometry from PubChem. Not evidence.

What the reference databases state

Statements

7 statements

7 statements · 2 reference databases · Subject: 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate · Sources: Human-GEM, Rhea

Order

(15R)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate is converted to 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoateCompoundRhea RHEA:50152Inferred only
(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate is converted to 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoateCompoundRhea RHEA:48636Inferred only
(15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate is converted to 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoateCompoundHuman-GEM MAR00990Inferred only
15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate is converted to (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoateCompoundRhea RHEA:23264Inferred only
(15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate is converted to 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoateCompoundRhea RHEA:23264Inferred only
(15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate is converted to 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoateCompoundRhea RHEA:23260Inferred only
(15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate is converted to 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoateCompoundHuman-GEM MAR00989Inferred only

Reactions

7 reactions

(15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate+NADP(3-)15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate+proton+NADPH(4-)
Reaction pageLeft to rightBalancedEC 1.1.1.232cytosol
Human-GEM MAR00989CC BY 4.0Reference data
(15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate+NAD(+)15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate+proton+NADH(2-)
Reaction pageLeft to rightBalancedEC 1.1.1.232cytosol
Human-GEM MAR00990CC BY 4.0Reference data
(15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate+NAD(1-)15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate+NADH(2-)+hydron
Catalysed by HPGD
Reaction pageLeft to rightBalanced
Rhea RHEA:23260CC BY 4.0Reference data
(15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate+NADP(3-)15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate+NADPH(4-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:23264CC BY 4.0Reference data
(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate+water
Catalysed by CYP1A1 or CYP1A2 or TBXAS1 or PTGIS or CYP1B1 or CYP2S1 or ALOXE3
Reaction pageLeft to rightBalanced
Rhea RHEA:48636CC BY 4.0Reference data
(15R)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate+water
Catalysed by ALOX15
Reaction pageLeft to rightBalanced
Rhea RHEA:50152CC BY 4.0Reference data
15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate+ATP(4-)+coenzyme A(4-)CHEBI:136578+AMP+diphosphate(3-)
Reaction pageDirection not assertedBalanced
Rhea RHEA:52364CC BY 4.0Reference data

Other names

10 names

Resolves to: 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate

Also called: (5Z,8Z,11Z,13E)-15-ketoeicosa-5,8,11,13-tetraenoate(5Z,8Z,11Z,13E)-15-oxo-5,8,11,13-eicosatetraenoate(5Z,8Z,11Z,13E)-15-oxoeicosa-5,8,11,13-tetraenoate15-KETE15-kete-ETE15-keto-(5Z,8Z,11Z,13E)-ETE15-oxo-(5Z,8Z,11Z,13E)-ETE15-oxo-5,8,11-cis-13-trans-eicosatetraenoate15-oxo-ETE
Systematic name: (5Z,8Z,11Z,13E)-15-oxoicosa-5,8,11,13-tetraenoate