Papers/PMID:41635453
Efficacy and safety of Ashwagandha (Withania somnifera) root extract on stress and weight management in adults: a prospective, randomized, double-blind, placebo-controlled study.
Journal of medicine and life2025The record
3 findings · 1 compound · 3 endpoints
What it reported
How to read these marksWhat moved
3 findings
Withania somnifera — decreases body mass
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.Finding“However, significantly greater reductions in body weight and BMI were observed at weeks 4, 12, and 24 (P < 0.0001) with ARE compared to PL.”
Quoted verbatim from Efficacy and safety of Ashwagandha (Withania somnifera) root extract on stress and weight management in adults: a prospective, randomized, double-blind, placebo-controlled study.. - Study
- RCT
- Participants
- 91
- Duration
- 6 months
- Dose
- 300 mg twice daily for 24 weeks
- Population
- Adults aged 19-65 years with BMI 25.0-39.9 kg/m2 (overweight or obese)
Efficacy and safety of Ashwagandha (Withania somnifera) root extract on stress and weight management in adults: a prospective, randomized, double-blind, placebo-controlled study.2025PMID:41635453Permalink
Withania somnifera — decreases body mass index
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.Finding“However, significantly greater reductions in body weight and BMI were observed at weeks 4, 12, and 24 (P < 0.0001) with ARE compared to PL.”
Quoted verbatim from Efficacy and safety of Ashwagandha (Withania somnifera) root extract on stress and weight management in adults: a prospective, randomized, double-blind, placebo-controlled study.. - Study
- RCT
- Participants
- 91
- Duration
- 6 months
- Dose
- 300 mg twice daily for 24 weeks
- Population
- Adults aged 19-65 years with BMI 25.0-39.9 kg/m2 (overweight or obese)
Efficacy and safety of Ashwagandha (Withania somnifera) root extract on stress and weight management in adults: a prospective, randomized, double-blind, placebo-controlled study.2025PMID:41635453Permalink
Withania somnifera — decreases perceived Stress Scale (PSS) score
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.Finding“The PSS-10 scores showed a mean reduction of -6.16 at week 24 in the ARE group, compared with -1.43 in the PL group (P < 0.001).”
Quoted verbatim from Efficacy and safety of Ashwagandha (Withania somnifera) root extract on stress and weight management in adults: a prospective, randomized, double-blind, placebo-controlled study.. - Study
- RCT
- Participants
- 91
- Duration
- 6 months
- Dose
- 300 mg twice daily for 24 weeks
- Population
- Adults aged 19-65 years with BMI 25.0-39.9 kg/m2 (overweight or obese)
Efficacy and safety of Ashwagandha (Withania somnifera) root extract on stress and weight management in adults: a prospective, randomized, double-blind, placebo-controlled study.2025PMID:41635453Permalink