Papers/PMID:41635453
Efficacy and safety of Ashwagandha (Withania somnifera) root extract on stress and weight management in adults: a prospective, randomized, double-blind, placebo-controlled study.
Journal of medicine and life2025The record
3 findings drawn from this paper, on 1 compound across 3 endpoints.
What it reported
How to read these marksWhat moved
3 findings
Withania somnifera — decreases body mass
Well establishedGrade A, Well established. Replicated human trial evidence, consistent direction.Finding“However, significantly greater reductions in body weight and BMI were observed at weeks 4, 12, and 24 (P < 0.0001) with ARE compared to PL.”
Quoted verbatim from Efficacy and safety of Ashwagandha (Withania somnifera) root extract on stress and weight management in adults: a prospective, randomized, double-blind, placebo-controlled study.. - Study
- RCT
- Participants
- 91
- Duration
- 6 months
- Dose
- 300 mg twice daily for 24 weeks
- Population
- Adults aged 19-65 years with BMI 25.0-39.9 kg/m2 (overweight or obese)
Withania somnifera — decreases body mass index
Well establishedGrade A, Well established. Replicated human trial evidence, consistent direction.Finding“However, significantly greater reductions in body weight and BMI were observed at weeks 4, 12, and 24 (P < 0.0001) with ARE compared to PL.”
Quoted verbatim from Efficacy and safety of Ashwagandha (Withania somnifera) root extract on stress and weight management in adults: a prospective, randomized, double-blind, placebo-controlled study.. - Study
- RCT
- Participants
- 91
- Duration
- 6 months
- Dose
- 300 mg twice daily for 24 weeks
- Population
- Adults aged 19-65 years with BMI 25.0-39.9 kg/m2 (overweight or obese)
Withania somnifera — decreases perceived Stress Scale (PSS) score
Well establishedGrade A, Well established. Replicated human trial evidence, consistent direction.Finding“The PSS-10 scores showed a mean reduction of -6.16 at week 24 in the ARE group, compared with -1.43 in the PL group (P < 0.001).”
Quoted verbatim from Efficacy and safety of Ashwagandha (Withania somnifera) root extract on stress and weight management in adults: a prospective, randomized, double-blind, placebo-controlled study.. - Study
- RCT
- Participants
- 91
- Duration
- 6 months
- Dose
- 300 mg twice daily for 24 weeks
- Population
- Adults aged 19-65 years with BMI 25.0-39.9 kg/m2 (overweight or obese)