Endpoint
Perceived Stress Scale (PSS) score
CAT:outcome/perceived-stress-scalereported in score (points)1 finding from 1 compound
What moved it
How to read these marks1 finding · 1 compound · by evidence strength
| Compound | Direction | Findings | Strongest evidence |
|---|---|---|---|
| Withania somnifera | down | 1 | Evidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers. |
Reported to move it
1 finding
Withania somnifera — decreases
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.Finding“The PSS-10 scores showed a mean reduction of -6.16 at week 24 in the ARE group, compared with -1.43 in the PL group (P < 0.001).”
Quoted verbatim from Efficacy and safety of Ashwagandha (Withania somnifera) root extract on stress and weight management in adults: a prospective, randomized, double-blind, placebo-controlled study.. - Study
- RCT
- Participants
- 91
- Duration
- 6 months
- Dose
- 300 mg twice daily for 24 weeks
- Population
- Adults aged 19-65 years with BMI 25.0-39.9 kg/m2 (overweight or obese)
Efficacy and safety of Ashwagandha (Withania somnifera) root extract on stress and weight management in adults: a prospective, randomized, double-blind, placebo-controlled study.2025PMID:41635453Permalink
How it is measured
Cohen Perceived Stress Scale total score (PSS-14, PSS-10, or PSS-4), self-completed, appraising the uncontrollability and unpredictability of life over the preceding month. Item count recorded with each finding and not optional, because the versions have different ranges.
Measured, not recorded
- Subject
- perceived stress scale (pss) score
- Measurements
- 2 measurements
- Recorded as a finding
- No
Show what was measured
Perceived Stress Scale (PSS) score
decreases, VL-G-E12 change -8.95(4.03) vs placebo -4.39(5.52) at day 60, n = 174
This change was also statistically significant (p < 0.05) by day 30 for the VL-G-E12 arm and in both the IP arms, VL-G-A57 and VL-G-E12, when compared to placebo (p < 0.0001) at day 60 (Table 3).
PMID:41656269 · one of two readings recorded this
Perceived Stress Scale (PSS) score
decreases, 38.6% reduction (group A) and 41.6% reduction (group B) vs 14.2% placebo, n = 126
Compared to group C, the mean PSS score significantly reduced as early as day 15 in group B and day 30 in group A.
PMID:41824889 · one of two readings recorded this
Sources cited
1 paper
- Subject
- perceived stress scale (pss) score
- Findings
- 1
- Papers
- 1