Papers/PMID:37660951
Dietary Glutamine and Glutamate in Relation to Cardiovascular Disease Incidence and Mortality in the United States Men and Women with Diabetes Mellitus.
The Journal of nutrition2023The record
2 findings · 1 compound · 2 endpoints
What it reported
How to read these marksWhat moved
2 findings
L-glutamine — decreases all-cause mortality
Evidence strength: very limited.Findingreplicated ×2“Higher intake of glutamine was associated with lower risk of CVD incidence, CVD mortality, and total mortality: comparing extreme quintiles, the hazard ratios (HRs) (95% confidence intervals [CIs]) were 0.88 (0.77, 0.99), 0.78 (0.65, 0.92), and 0.84 (0.76, 0.92), respectively (all P-trend < 0.05).”
Quoted verbatim from Dietary Glutamine and Glutamate in Relation to Cardiovascular Disease Incidence and Mortality in the United States Men and Women with Diabetes Mellitus.. - Study
- cohort
- Population
- Men and women with type 2 diabetes in the Nurses' Health Study and Health Professionals Follow-Up Study; dietary glutamine intake from food frequency questionnaires, highest versus lowest quintile
Effect 0.84 hazard ratio, 95% CI 0.76 to 0.92
Dietary Glutamine and Glutamate in Relation to Cardiovascular Disease Incidence and Mortality in the United States Men and Women with Diabetes Mellitus.2023PMID:3766095110.1016/j.tjnut.2023.08.031Permalink
L-glutamine — decreases incidence of cardiovascular disease (composite)
Evidence strength: very limited.Finding“Higher intake of glutamine was associated with lower risk of CVD incidence, CVD mortality, and total mortality: comparing extreme quintiles, the hazard ratios (HRs) (95% confidence intervals [CIs]) were 0.88 (0.77, 0.99), 0.78 (0.65, 0.92), and 0.84 (0.76, 0.92), respectively (all P-trend < 0.05).”
Quoted verbatim from Dietary Glutamine and Glutamate in Relation to Cardiovascular Disease Incidence and Mortality in the United States Men and Women with Diabetes Mellitus.. - Study
- cohort
- Population
- Men and women with type 2 diabetes in the Nurses' Health Study and Health Professionals Follow-Up Study; dietary glutamine intake from food frequency questionnaires, highest versus lowest quintile
Effect 0.88 hazard ratio, 95% CI 0.77 to 0.99
Dietary Glutamine and Glutamate in Relation to Cardiovascular Disease Incidence and Mortality in the United States Men and Women with Diabetes Mellitus.2023PMID:3766095110.1016/j.tjnut.2023.08.031Permalink