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Papers/PMID:33302116

The effect of calcium supplementation on blood pressure in non-pregnant women with previous pre-eclampsia: A randomized placebo-controlled study.

Pregnancy hypertension2021The record

2 findings · 1 compound · 2 endpoints

What it reported

How to read these marks

What moved

2 findings

  • Ca(2+) — decreases mean arterial pressure

    Evidence strength: moderate.Finding
    “There was a greater reduction in blood pressure in the calcium group compared with the placebo group for systolic (difference 3.1 mmHg, 95% CI 0.8 to 5.4) and mean arterial pressure (MAP) (difference 2.0 mmHg, 95% CI 0.1 to 3.8).”
    Quoted verbatim from The effect of calcium supplementation on blood pressure in non-pregnant women with previous pre-eclampsia: A randomized placebo-controlled study..
    Study
    RCT
    Dose
    500 mg elemental calcium daily as one chewable tablet vs identical placebo
    Population
    Non-pregnant women with pre-eclampsia or eclampsia in their most recent pregnancy, low habitual calcium intake (South Africa, Zimbabwe, Argentina); change in MAP at the 12-week visit; those not pregnant at that visit

    Effect 2 mean difference, 95% CI 0.1 to 3.8

    The effect of calcium supplementation on blood pressure in non-pregnant women with previous pre-eclampsia: A randomized placebo-controlled study.2021PMID:3330211610.1016/j.preghy.2020.11.012Permalink

  • Ca(2+) — decreases systolic blood pressure (setting unspecified)

    Evidence strength: moderate.Findingreplicated ×4
    “There was a greater reduction in blood pressure in the calcium group compared with the placebo group for systolic (difference 3.1 mmHg, 95% CI 0.8 to 5.4) and mean arterial pressure (MAP) (difference 2.0 mmHg, 95% CI 0.1 to 3.8).”
    Quoted verbatim from The effect of calcium supplementation on blood pressure in non-pregnant women with previous pre-eclampsia: A randomized placebo-controlled study..
    Study
    RCT
    Dose
    500 mg elemental calcium daily as one chewable tablet vs identical placebo
    Population
    Non-pregnant women with pre-eclampsia or eclampsia in their most recent pregnancy, low habitual calcium intake (South Africa, Zimbabwe, Argentina); change in blood pressure at the 12-week visit; those not pregnant at that visit

    Effect 3.1 mean difference, 95% CI 0.8 to 5.4

    The effect of calcium supplementation on blood pressure in non-pregnant women with previous pre-eclampsia: A randomized placebo-controlled study.2021PMID:3330211610.1016/j.preghy.2020.11.012Permalink