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Papers/PMID:32401318

Calcium supplementation for improving bone density in lactating women: a systematic review and meta-analysis of randomized controlled trials.

The American journal of clinical nutrition2020The record

1 finding · 1 compound · 1 endpoint · 1 null

What it reported

How to read these marks

Every finding here is a null result.

What did not

1 finding

  • Ca(2+) — no detected effect on lumbar spine bone mineral density

    Evidence strength: very limited.FindingNull resultreplicated ×1
    “Compared with control groups (placebo/no intervention), calcium supplementation (600/1000 mg/d) had no significant effect on BMD at the lumbar spine (WMD: 0.74%; 95% CI: -0.10%, 1.59%; I2 = 47%; 95% CI: 0%, 81%; n = 527 from 5 trials) or the forearm (WMD: 0.53%; 95% CI: -0.35%, 1.42%; I2 = 55%; 95% CI: 0%, 85%; n = 415 from 4 trials).”
    Quoted verbatim from Calcium supplementation for improving bone density in lactating women: a systematic review and meta-analysis of randomized controlled trials..
    Study
    meta-analysis
    Participants
    527
    Dose
    600/1000 mg/d calcium supplementation
    Population
    Lactating women; five randomised controlled trials, all at high risk of bias; percentage change in BMD

    Effect 0.74 mean difference, 95% CI -0.1 to 1.59

    Calcium supplementation for improving bone density in lactating women: a systematic review and meta-analysis of randomized controlled trials.2020PMID:3240131810.1093/ajcn/nqaa103Permalink