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Papers/PMID:24114400

The Auckland calcium study: 5-year post-trial follow-up.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2014The record

2 findings · 1 compound · 2 endpoints · 1 null

What it reported

How to read these marks

What moved

1 finding

  • Ca(2+) — decreases vertebral fracture incidence

    Evidence strength: very limited.Findingreplicated ×1
    “Over the 10-year period, there was no effect on total fracture (HR 0.90, 95% CI 0.75-1.07) or hip fracture incidence (1.40, 0.89-2.21), but significant reductions in forearm (0.62, 0.43-0.89) and vertebral fractures (0.52, 0.32-0.85) in those assigned to calcium.”
    Quoted verbatim from The Auckland calcium study: 5-year post-trial follow-up..
    Study
    RCT
    Dose
    1 g/day calcium citrate for 5 years
    Population
    Postmenopausal women in the Auckland calcium study, 10 years from randomisation (5 years of supplement, 5 years post-trial follow-up)

    Effect 0.52 hazard ratio, 95% CI 0.32 to 0.85

    The Auckland calcium study: 5-year post-trial follow-up.2014PMID:2411440010.1007/s00198-013-2526-zPermalink

What did not

1 finding

  • Ca(2+) — no detected effect on hip fracture incidence

    Evidence strength: very limited.FindingNull resultreplicated ×3
    “Over the 10-year period, there was no effect on total fracture (HR 0.90, 95% CI 0.75-1.07) or hip fracture incidence (1.40, 0.89-2.21), but significant reductions in forearm (0.62, 0.43-0.89) and vertebral fractures (0.52, 0.32-0.85) in those assigned to calcium.”
    Quoted verbatim from The Auckland calcium study: 5-year post-trial follow-up..
    Study
    RCT
    Dose
    1 g/day calcium citrate for 5 years
    Population
    Postmenopausal women in the Auckland calcium study, 10 years from randomisation (5 years of supplement, 5 years post-trial follow-up)

    Effect 1.4 hazard ratio, 95% CI 0.89 to 2.21

    The Auckland calcium study: 5-year post-trial follow-up.2014PMID:2411440010.1007/s00198-013-2526-zPermalink