Endpoint
Hip fracture incidence
CAT:outcome/hip-fracture-incidencereported in proportion1 finding from 1 compound
What moved it
How to read these marks1 finding · 1 compound · 1 null · by evidence strength
| Compound | Direction | Findings | Strongest evidence |
|---|---|---|---|
| Ca(2+) | no effect | 1 | Evidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers. |
Every finding here is a null result.
Measured, no effect detected
1 finding
Ca(2+) — no detected effect on
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.FindingNull result“The association between calcium administration and hip fracture [risk ratio (RR) 1.56; 95% confidence interval (CI), 0.91 to 2.69, I2=28%; P=0.11], vertebral fracture (RR 0.95; 95% CI, 0.82 to 1.10, I2=0%; P=0.49) or other fractures (RR 0.83; 95% CI 0.65 to 1.06, I2=0%; P=0.14) was not significant in comparison to either no treatment or placebo administration.”
Quoted verbatim from Role of calcium &/or vitamin D supplementation in preventing osteoporotic fracture in the elderly: A systematic review & meta-analysis.. - Study
- meta-analysis
- Population
- Adults older than 50 years with a previous history of fracture; pooled randomised trials of calcium supplementation against placebo or no treatment
Effect 1.56 risk ratio, 95% CI 0.91 to 2.69
Role of calcium &/or vitamin D supplementation in preventing osteoporotic fracture in the elderly: A systematic review & meta-analysis.2023PMID:37602580Permalink
How it is measured
Proportion of participants sustaining at least one incident fracture of the proximal femur (femoral neck or trochanteric region), ascertained by radiograph, hospital discharge record or adjudicated clinical report over the follow-up the source states. Whether fractures were adjudicated or self-reported is recorded with each finding.
Sources cited
1 paper
- Subject
- hip fracture incidence
- Findings
- 1
- Papers
- 1