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4,301–4,350 of 12,877 reactions from Human-GEM
3-carboxy-alpha-chromanol[e] =
ReversibleBalance undeterminableExchange/demand reactionsHuman-GEM MAR04407
fumarate[c] + H2O[c] = malate[c]
ReversibleBalancedEC 4.2.1.2Tricarboxylic acid cycle and glyoxylate/dicarboxylate metabolismHuman-GEM MAR04408
hepoxilin A3[e] =
ReversibleBalance undeterminableExchange/demand reactionsHuman-GEM MAR04409
fumarate[m] + H2O[m] = malate[m]
ReversibleBalancedEC 4.2.1.2Tricarboxylic acid cycle and glyoxylate/dicarboxylate metabolismHuman-GEM MAR04410
AMP[c] + fumarate[c] = adenylosuccinate[c]
ReversibleBalancedEC 4.3.2.2Purine metabolismHuman-GEM MAR04412
0.505626 alanine[c] + 0.35926 arginine[c] + 0.279425 asparagine[c] + 0.352607 aspartate[c] + 20.704451 ATP[c] + 0.020401 cholesterol[c] + 0.011658 CL pool[c] + 0.039036 CTP[c] + 0.046571 cysteine[c] + 0.013183 dATP[n] + 0.009442 dCTP[n] + 0.009898 dGTP[n] + 0.013091 dTTP[n] + 0.275194 glucose-6-phosphate[c] + 0.385872 glutamate[c] + 0.325996 glutamine[c] + 0.538891 glycine[c] + 0.036117 GTP[c] + 20.650823 H2O[c] + 0.126406 histidine[c] + 0.286078 isoleucine[c] + 0.545544 leucine[c] + 0.592114 lysine[c] + 0.153018 methionine[c] + 0.154463 PC-LD pool[c] + 0.055374 PE-LD pool[c] + 0.002914 PG-CL pool[c] + 0.259466 phenylalanine[c] + 0.023315 PI pool[c] + 0.412484 proline[c] + 0.005829 PS-LD pool[c] + 0.392525 serine[c] + 0.017486 SM pool[c] + 0.31269 threonine[c] + 0.013306 tryptophan[c] + 0.159671 tyrosine[c] + 0.053446 UTP[c] + 0.352607 valine[c] = 20.650823 ADP[c] + 20.650823 H+[c] + 20.650823 Pi[c] + biomass[c]
BlockedBalance undeterminableArtificial reactionsHuman-GEM MAR04413
ATP[c] + galactose[c] = ADP[c] + galactose-1-phosphate[c] + H+[c]
Left to rightBalancedEC 2.7.1.6Galactose metabolismHuman-GEM MAR04414
H2O[e] + lactose[e] = galactose[e] + glucose[e]
Left to rightBalancedEC 3.2.1.23, 3.2.1.108Galactose metabolismHuman-GEM MAR04415
galactosylglycerol[e] + H2O[e] = galactose[e] + glycerol[e]
Left to rightBalancedEC 3.2.1.22, 3.2.1.23Galactose metabolismHuman-GEM MAR04416
H2O[c] + IMP[c] = inosine[c] + Pi[c]
Left to rightBalancedEC 3.1.3.5Purine metabolismHuman-GEM MAR04417
hypoxanthine[c] + PRPP[c] = IMP[c] + PPi[c]
Left to rightBalancedEC 2.4.2.8Purine metabolismHuman-GEM MAR04418
GMP[c] + H+[c] + NADPH[c] = IMP[c] + NADP+[c] + NH3[c]
Left to rightBalancedEC 1.7.1.7Purine metabolismHuman-GEM MAR04419
ADP[m] + dATP[m] = ATP[m] + dADP[m]
Left to rightBalancedEC 2.7.4.6Purine metabolismHuman-GEM MAR04420
dADP[c] + H+[c] + PEP[c] = dATP[c] + pyruvate[c]
Left to rightBalancedEC 2.7.1.40Purine metabolismHuman-GEM MAR04421
H+[e] + ornithine[e] = CO2[e] + putrescine[e]
Left to rightBalancedEC 4.1.1.17Arginine and proline metabolismHuman-GEM MAR04422
H2O[e] + O2[e] + putrescine[e] = 4-aminobutanal[e] + H+[e] + H2O2[e] + NH3[e]
Left to rightBalancedEC 1.4.3.10, 1.4.3.21, 1.4.3.22Arginine and proline metabolismHuman-GEM MAR04423
agmatine[m] + H2O[m] = putrescine[m] + urea[m]
Left to rightBalancedEC 3.5.3.11Arginine and proline metabolismHuman-GEM MAR04424
ATP[c] + beta-alanine[c] + histidine[c] = AMP[c] + carnosine[c] + H+[c] + PPi[c]
Left to rightBalancedEC 6.3.2.11Beta-alanine metabolismHuman-GEM MAR04425
acetylcarnosine[c] + CoA[c] + H+[c] = acetyl-CoA[c] + carnosine[c]
ReversibleBalancedEC 2.3.1.255Histidine metabolismHuman-GEM MAR04426
carnosine[c] + H2O[c] = beta-alanine[c] + histidine[c]
Left to rightBalancedEC 3.4.13.18, 3.4.13.20Beta-alanine metabolismHuman-GEM MAR04427
H+[c] + histidine[c] = CO2[c] + histamine[c]
Left to rightBalancedEC 4.1.1.22, 4.1.1.28Histidine metabolismHuman-GEM MAR04428
histamine[c] + SAM[c] = H+[c] + N-methylhistamine[c] + SAH[c]
Left to rightBalancedEC 2.1.1.8Histidine metabolismHuman-GEM MAR04429
H2O[c] + N-methylhistamine[c] + O2[c] = H+[c] + H2O2[c] + methylimidazole-acetaldehyde[c] + NH3[c]
Left to rightBalancedEC 1.4.3.4Histidine metabolismHuman-GEM MAR04430
H2O[c] + methylimidazole-acetaldehyde[c] + NAD+[c] = 2 H+[c] + methylimidazoleacetic acid[c] + NADH[c]
Left to rightBalancedEC 1.2.1.5Histidine metabolismHuman-GEM MAR04431
methylimidazoleacetic acid[c] = methylimidazoleacetic acid[e]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR04432
glutathionyl-leukotriene C4[c] + HCO3-[c] + histamine[e] = glutathionyl-leukotriene C4[e] + HCO3-[e] + histamine[c]
ReversibleBalance undeterminableTransportTransport reactionsHuman-GEM MAR04433
HCO3-[c] + histamine[e] + S-glutathionyl-2-4-dinitrobenzene[c] = HCO3-[e] + histamine[c] + S-glutathionyl-2-4-dinitrobenzene[e]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR04434
HCO3-[c] + histamine[e] + S-glutathionyl-ethacrynic acid[c] = HCO3-[e] + histamine[c] + S-glutathionyl-ethacrynic acid[e]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR04435
GSH[c] + HCO3-[c] + histamine[e] = GSH[e] + HCO3-[e] + histamine[c]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR04436
histidine[c] = H+[c] + NH3[c] + urocanate[c]
Left to rightBalancedEC 4.3.1.3Histidine metabolismHuman-GEM MAR04437
tiglyl-CoA[m] = tiglyl-CoA[c]
ReversibleBalancedTransportFatty acid oxidationHuman-GEM MAR04438
(R)-3-hydroxybutanoyl-CoA[m] = (R)-3-hydroxybutanoyl-CoA[c]
ReversibleBalancedTransportFatty acid oxidationHuman-GEM MAR04439
5,10-methenyl-THF[m] + NADH[m] = 5,10-methylene-THF[m] + NAD+[m]
ReversibleBalancedEC 1.5.1.15Folate metabolismHuman-GEM MAR04440
ATP[c] + CoA[c] + adipic acid[c] = AMP[c] + PPi[c] + adipoyl-CoA[c]
Left to rightBalancedFatty acid oxidationHuman-GEM MAR04441
5,10-methenyl-THF[c] + NADPH[c] = 5,10-methylene-THF[c] + NADP+[c]
ReversibleBalancedEC 1.5.1.5Folate metabolismHuman-GEM MAR04442
adipic acid[x] = adipic acid[c]
ReversibleBalancedTransportFatty acid oxidationHuman-GEM MAR04443
5,10-methenyl-THF[m] + NADPH[m] = 5,10-methylene-THF[m] + NADP+[m]
ReversibleBalancedEC 1.5.1.5Folate metabolismHuman-GEM MAR04444
L-carnitine[x] + adipoyl-CoA[x] = CoA[x] + Adipoyl Carnitine[x]
ReversibleBalancedEC 2.3.1.137Fatty acid oxidationHuman-GEM MAR04445
5,10-methylene-THF[c] + 2 H+[c] + NADPH[c] = 5-methyl-THF[c] + NADP+[c]
Left to rightBalancedEC 1.5.1.20Folate metabolismHuman-GEM MAR04446
H2O[x] + adipoyl-CoA[x] = CoA[x] + H+[x] + adipic acid[x]
Left to rightBalancedEC 3.1.2.-Fatty acid oxidationHuman-GEM MAR04447
5,10-methylene-THF[c] + 2 H+[c] + NADH[c] = 5-methyl-THF[c] + NAD+[c]
Left to rightBalancedEC 1.5.1.20Folate metabolismHuman-GEM MAR04448
GMP[c] + H2O[c] = guanosine[c] + Pi[c]
Left to rightBalancedEC 3.1.3.5Purine metabolismHuman-GEM MAR04449
GMP[e] + H2O[e] = guanosine[e] + Pi[e]
Left to rightBalancedEC 3.1.3.5Purine metabolismHuman-GEM MAR04450
ADP[m] + GMP[m] + H+[m] = ATP[m] + guanosine[m]
Left to rightBalancedEC 2.7.1.73Purine metabolismHuman-GEM MAR04451
guanine[c] + PRPP[c] = GMP[c] + PPi[c]
Left to rightBalancedEC 2.4.2.8Purine metabolismHuman-GEM MAR04452
ATP[c] + NH3[c] + xanthosine-5-phosphate[c] = AMP[c] + GMP[c] + H+[c] + PPi[c]
Left to rightBalancedEC 6.3.5.2Purine metabolismHuman-GEM MAR04453
citrate[c] = isocitrate[c]
ReversibleBalancedEC 4.2.1.3Tricarboxylic acid cycle and glyoxylate/dicarboxylate metabolismHuman-GEM MAR04454
decanoyl-CoA[c] + L-carnitine[c] = CoA[c] + Decanoyl Carnitine[c]
ReversibleBalancedEC 2.3.1.21Fatty acid oxidationHuman-GEM MAR04457
cis-aconitate[m] + H2O[m] = citrate[m]
ReversibleBalancedEC 4.2.1.3Tricarboxylic acid cycle and glyoxylate/dicarboxylate metabolismHuman-GEM MAR04458
ATP[c] + H+[c] + propanoate[c] = PPi[c] + propinol adenylate[c]
Left to rightBalancedEC 6.2.1.1, 6.2.1.17Propanoate metabolismHuman-GEM MAR04459