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Subsystem: Histidine metabolism Remove
20 reactions in Histidine metabolism
acetylcarnosine[c] + CoA[c] + H+[c] = acetyl-CoA[c] + carnosine[c]
ReversibleBalancedEC 2.3.1.255Human-GEM MAR04426
H+[c] + histidine[c] = CO2[c] + histamine[c]
Left to rightBalancedEC 4.1.1.22, 4.1.1.28Human-GEM MAR04428
histamine[c] + SAM[c] = H+[c] + N-methylhistamine[c] + SAH[c]
Left to rightBalancedEC 2.1.1.8Human-GEM MAR04429
H2O[c] + N-methylhistamine[c] + O2[c] = H+[c] + H2O2[c] + methylimidazole-acetaldehyde[c] + NH3[c]
Left to rightBalancedEC 1.4.3.4Human-GEM MAR04430
H2O[c] + methylimidazole-acetaldehyde[c] + NAD+[c] = 2 H+[c] + methylimidazoleacetic acid[c] + NADH[c]
Left to right
histidine[c] = H+[c] + NH3[c] + urocanate[c]
Left to rightBalancedEC 4.3.1.3Human-GEM MAR04437
4-aminobutyrate[c] + ATP[c] + histidine[c] = AMP[c] + H+[c] + homocarnosine[c] + PPi[c]
Left to rightBalancedEC 6.3.2.11Human-GEM MAR04606
H2O[c] + homocarnosine[c] = 4-aminobutyrate[c] + histidine[c]
Left to rightBalancedEC 3.4.13.18, 3.4.13.20Human-GEM MAR04607
5-formiminotetrahydrofolate[c] + glutamate[c] = H+[c] + N-formimino-L-glutamate[c] + THF[c]
ReversibleBalancedEC 2.1.2.5Human-GEM MAR04658
4-imidazolone-5-propanoate[c] + H2O[c] = H+[c] + N-formimino-L-glutamate[c]
Left to rightBalancedEC 3.5.2.7Human-GEM MAR04660
H2O[c] + urocanate[c] = 4-imidazolone-5-propanoate[c]
Left to rightBalancedEC 4.2.1.49Human-GEM MAR04712
2 H2O[c] + S-[2-carboxy-1-(1H-imidazol-4-yl)ethyl]glutathione[c] = glutamate[c] + glycine[c] + S-[2-carboxy-1-(1H-imidazol-4-yl)ethyl]-L-cysteine[c]
ReversibleBalancedEC 3.5.1.-Human-GEM MAR05336
GSH[c] + urocanate[c] = S-[2-carboxy-1-(1H-imidazol-4-yl)ethyl]glutathione[c]
ReversibleBalancedEC 2.5.1.-Human-GEM MAR05337
acetyl-CoA[c] + S-[2-carboxy-1-(1H-imidazol-4-yl)ethyl]-L-cysteine[c] = CoA[c] + H+[c] + N-acetyl-S-[2-carboxy-1-(1H-imidazol-4-yl)ethyl]-L-cysteine[c]
Left to rightBalancedEC 2.3.1.199Human-GEM MAR05338
H2O[c] + N-acetyl-S-[2-carboxy-1-(1H-imidazol-4-yl)ethyl]-L-cysteine[c] = acetate[c] + S-[2-carboxy-1-(1H-imidazol-4-yl)ethyl]-L-cysteine[c]
ReversibleBalancedEC 3.5.1.-Human-GEM MAR05339
H2O[c] + S-[2-carboxy-1-(1H-imidazol-4-yl)ethyl]-L-cysteine[c] = NH4+[c] + S-[2-carboxy-1-(1H-imidazol-4-yl)ethyl]-3-thiolactate[c]
Left to rightBalancedEC 3.5.1.-Human-GEM MAR05340
H2O[c] + histamine[c] + O2[c] = H+[c] + H2O2[c] + imidazole-4-acetaldehyde[c] + NH3[c]
Left to rightBalancedEC 1.4.3.21, 1.4.3.22Human-GEM MAR08783
H2O[c] + imidazole-4-acetaldehyde[c] + NAD+[c] = 2 H+[c] + imidazole-4-acetate[c] + NADH[c]
Left to rightBalancedEC 1.2.1.3Human-GEM MAR08784
H2O[m] + imidazole-4-acetaldehyde[m] + NAD+[m] = 2 H+[m] + imidazole-4-acetate[m] + NADH[m]
Left to rightBalancedEC 1.2.1.4, 1.2.1.5Human-GEM MAR08786
histidine[c] + SAM[c] = H+[c] + SAH[c] + 3-Methylhistidine[c]
ReversibleBalancedEC 2.1.1.-Human-GEM MAR09939