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3,701–3,750 of 12,877 reactions from Human-GEM
H2O[g] + PS-LD pool[g] = H+[g] + phosphatidate-LD-PS pool[g] + serine[g]
Left to rightBalance undeterminableEC 3.1.4.4Glycerophospholipid metabolismHuman-GEM MAR03791
2-methyl-3-oxopropanoate[m] + glutamate[m] = AKG[m] + D-3-amino-isobutanoate[m]
ReversibleBalancedEC 2.6.1.22, 2.6.1.40Valine, leucine, and isoleucine metabolismHuman-GEM MAR03792
2-methyl-3-oxopropanoate[m] + alanine[m] = D-3-amino-isobutanoate[m] + pyruvate[m]
ReversibleBalancedEC 2.6.1.40Pyrimidine metabolismHuman-GEM MAR03793
CoA[m] + H+[m] + N-acetyl-L-alanine[m] = acetyl-CoA[m] + alanine[m]
ReversibleBalancedEC 2.3.1.1Glycine, serine and threonine metabolismHuman-GEM
2-methyl-3-oxopropanoate[m] + CoA[m] + NAD+[m] = CO2[m] + NADH[m] + propanoyl-CoA[m]
Left to rightBalancedEC 1.2.1.27Valine, leucine, and isoleucine metabolismHuman-GEM MAR03795
AMP[m] + H+[m] + propanoyl-CoA[m] = CoA[m] + propinol adenylate[m]
ReversibleBalancedEC 6.2.1.1, 6.2.1.17Valine, leucine, and isoleucine metabolismHuman-GEM MAR03796
ATP[m] + CoA[m] + propanoate[m] = AMP[m] + PPi[m] + propanoyl-CoA[m]
Left to rightBalancedEC 6.2.1.17Propanoate metabolismHuman-GEM MAR03797
H2O[r] + PS-LD pool[r] = H+[r] + phosphatidate-LD-PS pool[r] + serine[r]
Left to rightBalance undeterminableEC 3.1.4.4Glycerophospholipid metabolismHuman-GEM MAR03798
H2O[m] + propanoyl-CoA[m] = CoA[m] + H+[m] + propanoate[m]
Left to rightBalancedEC 3.1.2.2Bile acid biosynthesisHuman-GEM MAR03799
2-oxobutyrate[m] + H+[m] + thiamin-PP[m] = CO2[m] + 2-(1-hydroxypropyl)thiamine diphosphate[m]
Left to rightBalance undeterminableEC 1.2.4.4Propanoate metabolismHuman-GEM MAR03800
6,7-dihydro-5-oxo-12-epi-LTB4[m] + ATP[m] + CoA[m] = 5-oxo-12(R)-hydroxy-eicosa-(8E,10E,14Z)-trienoyl-CoA[m] + AMP[m] + PPi[m]
Left to rightBalancedEC 6.2.1.3Eicosanoid metabolismHuman-GEM MAR03801
AKG[m] + 2 H+[m] + NADH[m] + NH3[m] = glutamate[m] + H2O[m] + NAD+[m]
ReversibleBalancedEC 1.4.1.3Alanine, aspartate and glutamate metabolismHuman-GEM MAR03802
6,7-dihydro-5-oxo-12-epi-LTB4[r] + ATP[r] + CoA[r] = 5-oxo-12(R)-hydroxy-eicosa-(8E,10E,14Z)-trienoyl-CoA[r] + AMP[r] + PPi[r]
Left to rightBalancedEC 6.2.1.3Eicosanoid metabolismHuman-GEM MAR03803
AKG[m] + 2 H+[m] + NADPH[m] + NH3[m] = glutamate[m] + H2O[m] + NADP+[m]
ReversibleBalancedEC 1.4.1.3Alanine, aspartate and glutamate metabolismHuman-GEM MAR03804
6,7-dihydro-5-oxo-12-epi-LTB4[x] + ATP[x] + CoA[x] = 5-oxo-12(R)-hydroxy-eicosa-(8E,10E,14Z)-trienoyl-CoA[x] + AMP[x] + PPi[x]
Left to rightBalancedEC 6.2.1.3Eicosanoid metabolismHuman-GEM MAR03805
glutamate[m] + 2 H+[m] + NADH[m] = H2O[m] + L-glutamate 5-semialdehyde[m] + NAD+[m]
ReversibleBalancedEC 1.2.1.88Arginine and proline metabolismHuman-GEM MAR03806
AKG[m] + ornithine[m] = glutamate[m] + L-glutamate 5-semialdehyde[m]
ReversibleBalancedEC 2.6.1.13Arginine and proline metabolismHuman-GEM MAR03807
3(S),12(R)-dihydroxy-5-oxo-eicosa-(8E,10E,14Z)-trienoyl-CoA[c] + NAD+[c] = 3,5-dioxo-12(R)-hydroxy-eicosa-(8E,10E,14Z)-trienoyl-CoA[c] + H+[c] + NADH[c]
ReversibleBalancedEC 1.1.1.35Eicosanoid metabolismHuman-GEM MAR03808
citrulline[m] + H+[m] + Pi[m] = carbamoyl-phosphate[m] + ornithine[m]
ReversibleBalancedEC 2.1.3.3Arginine and proline metabolismHuman-GEM MAR03809
3-oxo-10(R)-hydroxy-octadeca-(6E,8E,12Z)-trienoyl-CoA[c] + H2O[c] = 3-oxo-10(R)-hydroxy-octadeca-(6E,8E,12Z)-trienoate[c] + CoA[c] + H+[c]
ReversibleBalancedEC 3.1.2.2Eicosanoid metabolismHuman-GEM MAR03810
aspartate[c] + ATP[c] + citrulline[c] = AMP[c] + argininosuccinate[c] + H+[c] + PPi[c]
Left to rightBalancedEC 6.3.4.5Alanine, aspartate and glutamate metabolismHuman-GEM MAR03811
3(S),12(S)-dihydroxy-5-oxo-eicosa-(8E,10E,14Z)-trienoyl-CoA[c] + NAD+[c] = 3,5-dioxo-12(S)-hydroxy-eicosa-(8E,10E,14Z)-trienoyl-CoA[c] + H+[c] + NADH[c]
ReversibleBalancedEC 1.1.1.35Eicosanoid metabolismHuman-GEM MAR03812
arginine[c] + fumarate[c] = argininosuccinate[c]
ReversibleBalancedEC 4.3.2.1Alanine, aspartate and glutamate metabolismHuman-GEM MAR03813
3-oxo-10(S)-hydroxy-octadeca-(6E,8E,12Z)-trienoyl-CoA[c] + H2O[c] = 3-oxo-10(S)-hydroxy-octadeca-(6E,8E,12Z)-trienoate[c] + CoA[c] + H+[c]
ReversibleBalancedEC 3.1.2.2Eicosanoid metabolismHuman-GEM MAR03814
3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanate[c] + 2 H+[c] + NADH[c] = 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al[c] + H2O[c] + NAD+[c]
ReversibleBalancedEC 1.2.1.3Bile acid biosynthesisHuman-GEM MAR03815
arginine[c] + H2O[c] = ornithine[c] + urea[c]
Left to rightBalancedEC 3.5.3.1Arginine and proline metabolismHuman-GEM MAR03816
3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanate[m] + 2 H+[m] + NADH[m] = 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al[m] + H2O[m] + NAD+[m]
Left to rightBalancedEC 1.2.1.3Bile acid biosynthesisHuman-GEM MAR03817
L-glutamate 5-semialdehyde[c] = L-glutamate 5-semialdehyde[m]
ReversibleBalancedTransportTransport reactionsHuman-GEM MAR03818
1-pyrroline-5-carboxylate[c] + H+[c] + H2O[c] = L-glutamate 5-semialdehyde[c]
ReversibleBalancedEC 1.2.1.88Arginine and proline metabolismHuman-GEM MAR03819
1-pyrroline-5-carboxylate[m] + H+[m] + H2O[m] = L-glutamate 5-semialdehyde[m]
ReversibleBalancedEC 1.2.1.88Arginine and proline metabolismHuman-GEM MAR03820
3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanate[r] + 2 H+[r] + NADH[r] = 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al[r] + H2O[r] + NAD+[r]
ReversibleBalancedEC 1.2.1.3Bile acid biosynthesisHuman-GEM MAR03821
1-pyrroline-5-carboxylate[m] + 2 H2O[m] + NAD+[m] = glutamate[m] + H+[m] + NADH[m]
Left to rightBalancedEC 1.2.1.88Alanine, aspartate and glutamate metabolismHuman-GEM MAR03822
(S)-3-hydroxy-2-methylbutyryl-CoA[m] + NAD+[m] = 2-methylacetoacetyl-CoA[m] + H+[m] + NADH[m]
ReversibleBalancedEC 1.1.1.178, 1.1.1.35Valine, leucine, and isoleucine metabolismHuman-GEM MAR03823
1-alkyl-2-lysoglycerol-3-phosphocholine[c] + H2O[c] = choline[c] + H+[c] + 1-Alkyl-Sn-Glycerol 3-Phosphate[c]
Left to rightBalance undeterminableEC 1.14.14.1Glycerophospholipid metabolismHuman-GEM MAR03824
aspartate[m] + glutamate[c] + H+[i] = aspartate[c] + glutamate[m] + H+[m]
Left to rightBalancedTransportTransport reactionsHuman-GEM MAR03825
alpha-CEHC-glucuronide[e] + H2O[e] = 3-carboxy-alpha-chromanol[e] + glucuronate[e] + H+[e]
ReversibleBalancedEC 3.2.1.31MiscellaneousHuman-GEM MAR03826
AKG[m] + aspartate[m] = glutamate[m] + OAA[m]
ReversibleBalancedEC 2.6.1.1Alanine, aspartate and glutamate metabolismHuman-GEM MAR03827
alpha-CEHC-glucuronide[l] + H2O[l] = 3-carboxy-alpha-chromanol[l] + glucuronate[l] + H+[l]
ReversibleBalancedEC 3.2.1.31MiscellaneousHuman-GEM MAR03828
AKG[c] + aspartate[c] = glutamate[c] + OAA[c]
ReversibleBalancedEC 2.6.1.1Alanine, aspartate and glutamate metabolismHuman-GEM MAR03829
9,10-12,13-diepoxy-octadecanoate[c] = 12,13-epoxy-9-alkoxy-(10E)-octadecenoate[c] + H+[c]
Left to rightUnbalancedEC 4.2.1.17Linoleate metabolismHuman-GEM MAR03830
arginine[c] + H2O[c] = citrulline[c] + H+[c] + NH3[c]
Left to rightBalancedEC 3.5.3.6Arginine and proline metabolismHuman-GEM MAR03832
1-pyrroline-5-carboxylate[c] + 2 H+[c] + NADPH[c] = NADP+[c] + proline[c]
Left to rightBalancedEC 1.5.1.2Arginine and proline metabolismHuman-GEM MAR03833
prostaglandin J2[m] = delta-12-prostaglandin J2[m]
ReversibleBalancedEC 1.5.1.38, 1.5.1.39, 1.5.1.41Eicosanoid metabolismHuman-GEM MAR03834
1-pyrroline-5-carboxylate[c] + 2 H+[c] + NADH[c] = NAD+[c] + proline[c]
Left to rightBalancedEC 1.5.1.2Arginine and proline metabolismHuman-GEM MAR03835
prostaglandin J2[r] = delta-12-prostaglandin J2[r]
ReversibleBalancedEicosanoid metabolismHuman-GEM MAR03836
1-pyrroline-5-carboxylate[m] + 2 H+[m] + NADH[m] = NAD+[m] + proline[m]
Left to rightBalancedEC 1.5.1.2Arginine and proline metabolismHuman-GEM MAR03837
3-phospho-D-glycerate[c] + NAD+[c] = 3-phosphonooxypyruvate[c] + H+[c] + NADH[c]
ReversibleBalancedEC 1.1.1.95Glycine, serine and threonine metabolismHuman-GEM MAR03839
10,11-dihydro-12-epi-LTB4[c] + H+[c] + NADPH[c] + O2[c] = 20-OH-10,11-dihydro-LTB4[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.14.94Eicosanoid metabolismHuman-GEM MAR03840
3-phosphonooxypyruvate[c] + glutamate[c] = 3-phosphoserine[c] + AKG[c]
ReversibleBalancedEC 2.6.1.52Glycine, serine and threonine metabolismHuman-GEM MAR03841
10,11-dihydro-12-epi-LTB4[r] + H+[r] + NADPH[r] + O2[r] = 20-OH-10,11-dihydro-LTB4[r] + H2O[r] + NADP+[r]
Left to rightBalancedEC 1.14.14.94Eicosanoid metabolismHuman-GEM MAR03842