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3,501–3,550 of 12,877 reactions from Human-GEM
cholesterol-ester-13,16,19-doco[l] + H2O[l] = 13,16,19-docosatrienoic acid[l] + cholesterol[l] + H+[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03583
cholesterol-ester-10,13,16,19-docosa[l] + H2O[l] = 10,13,16,19-docosatetraenoic acid[l] + cholesterol[l] + H+[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03584
cholesterol-ester-12,15,18,21-tetracosa[l] + H2O[l] = 12,15,18,21-tetracosatetraenoic acid[l] + cholesterol[l] + H+[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03585
cholesterol-ester-lin[l] + H2O[l] = cholesterol[l] + H+[l] + linoleate[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol esters
cholesterol-ester-gamma-lin[l] + H2O[l] = cholesterol[l] + gamma-linolenate[l] + H+[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03587
cholesterol-ester-dihomo-gamma[l] + H2O[l] = cholesterol[l] + dihomo-gamma-linolenate[l] + H+[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03588
cholesterol-ester-arach[l] + H2O[l] = arachidonate[l] + cholesterol[l] + H+[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03589
cholesterol-ester-7,10,13,16-docosa[l] + H2O[l] = adrenic acid[l] + cholesterol[l] + H+[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03590
cholesterol-ester-9,12,15,18-tetraco[l] + H2O[l] = (9Z,12Z,15Z,18Z)-TTA[l] + cholesterol[l] + H+[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03591
cholesterol-ester-6,9,12,15,18-tetraco[l] + H2O[l] = (6Z,9Z,12Z,15Z,18Z)-TPA[l] + cholesterol[l] + H+[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03592
cholesterol-ester-4,7,10,13,16-docosa[l] + H2O[l] = (4Z,7Z,10Z,13Z,16Z)-DPA[l] + cholesterol[l] + H+[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03593
cholesterol-ester-11,14-eicosa[l] + H2O[l] = (11Z,14Z)-eicosadienoic acid[l] + cholesterol[l] + H+[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03594
cholesterol-ester-13,16-docosa[l] + H2O[l] = (13Z,16Z)-docosadienoic acid[l] + cholesterol[l] + H+[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03595
cholesterol-ester-10,13,16-docosa[l] + H2O[l] = 10,13,16-docosatriynoic acid[l] + cholesterol[l] + H+[l]
Left to rightBalancedEC 3.1.1.13Formation and hydrolysis of cholesterol estersHuman-GEM MAR03596
cholesterol-ester pool[l] = cholesterol-ester pool[r]
Left to rightBalance undeterminableTransportTransport reactionsHuman-GEM MAR03597
CO2[c] + 3 lanosterol[c] = 3 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol[c] + 2 H2O[c] + 4 One Carbon Unit[c]
Left to rightBalancedCholesterol metabolismHuman-GEM MAR03598
H+[c] + L-dopachrome[c] + NADH[c] = 2-carboxy-2,3-dihydro-5,6-dihydroxyindole[c] + NAD+[c]
ReversibleBalancedTyrosine metabolismHuman-GEM MAR03599
5-alpha-dihydrotestosterone[l] + H+[l] + sulfate[l] = 5alpha-dihydrotestosterone-sulfate[l] + H2O[l]
ReversibleBalancedEC 3.1.6.2Androgen metabolismHuman-GEM MAR03600
5-alpha-dihydrotestosterone[r] + H+[r] + sulfate[r] = 5alpha-dihydrotestosterone-sulfate[r] + H2O[r]
ReversibleBalancedEC 3.1.6.2Androgen metabolismHuman-GEM MAR03601
androsterone[l] + H+[l] + sulfate[l] = androsterone sulfate[l] + H2O[l]
ReversibleBalancedEC 3.1.6.2Androgen metabolismHuman-GEM MAR03602
androsterone[r] + H+[r] + sulfate[r] = androsterone sulfate[r] + H2O[r]
ReversibleBalancedEC 3.1.6.2Androgen metabolismHuman-GEM MAR03603
H+[r] + malonyl-CoA[r] + oleoyl-CoA[r] = 3-oxo-11-cis-eicosenoyl-CoA[r] + CO2[r] + CoA[r]
Left to rightBalancedEC 2.3.1.199Fatty acid biosynthesisHuman-GEM MAR03604
(11Z)-eicosenoyl-CoA[r] + H+[r] + malonyl-CoA[r] = 3-oxo-13cis-docosenoyl-CoA[r] + CO2[r] + CoA[r]
Left to rightBalancedEC 2.3.1.199Fatty acid biosynthesisHuman-GEM MAR03605
(13Z)-docosenoyl-CoA[r] + H+[r] + malonyl-CoA[r] = 3-oxo-cis-15-tetracosaenoyl-CoA[r] + CO2[r] + CoA[r]
Left to rightBalancedEC 2.3.1.199Fatty acid biosynthesisHuman-GEM MAR03606
3-oxo-11-cis-eicosenoyl-CoA[r] + H+[r] + NADPH[r] = 3(S)-hydroxy-11-cis-eicosenoyl-CoA[r] + NADP+[r]
ReversibleBalancedEC 2.3.1.199Fatty acid biosynthesisHuman-GEM MAR03607
3(S)-hydroxy-11-cis-eicosenoyl-CoA[r] = H2O[r] + trans,cis-2,11-eicosadienoyl-CoA[r]
ReversibleBalancedEC 2.3.1.199Fatty acid biosynthesisHuman-GEM MAR03608
H+[r] + NADPH[r] + trans,cis-2,11-eicosadienoyl-CoA[r] = (11Z)-eicosenoyl-CoA[r] + NADP+[r]
ReversibleBalancedEC 2.3.1.199Fatty acid biosynthesisHuman-GEM MAR03609
3-oxo-13cis-docosenoyl-CoA[r] + H+[r] + NADPH[r] = 3(S)-hydroxy-13-cis-docosenoyl-CoA[r] + NADP+[r]
ReversibleBalancedEC 2.3.1.199Fatty acid biosynthesisHuman-GEM MAR03610
3(S)-hydroxy-13-cis-docosenoyl-CoA[r] = H2O[r] + trans,cis-2,13-docosadienoyl-CoA[r]
ReversibleBalancedEC 2.3.1.199Fatty acid biosynthesisHuman-GEM MAR03611
H+[r] + NADPH[r] + trans,cis-2,13-docosadienoyl-CoA[r] = (13Z)-docosenoyl-CoA[r] + NADP+[r]
ReversibleBalancedEC 2.3.1.199Fatty acid biosynthesisHuman-GEM MAR03612
hordenine[g] + O2[g] = H2O[g] + N,N-dimethyldopaminequinone[g]
Left to rightBalancedEC 1.14.18.1Tyrosine metabolismHuman-GEM MAR03613
hordenine[l] + O2[l] = H2O[l] + N,N-dimethyldopaminequinone[l]
Left to rightBalancedEC 1.14.18.1Tyrosine metabolismHuman-GEM MAR03614
3-oxo-cis-15-tetracosaenoyl-CoA[r] + H+[r] + NADPH[r] = 3(S)-hydroxy-cis-15-tetracosaenoyl-CoA[r] + NADP+[r]
ReversibleBalancedEC 1.1.1.35Fatty acid biosynthesisHuman-GEM MAR03615
3(S)-hydroxy-cis-15-tetracosaenoyl-CoA[r] = H2O[r] + trans,cis-2,15-tetracosadienoyl-CoA[r]
ReversibleBalancedEC 1.1.1.35Fatty acid biosynthesisHuman-GEM MAR03616
H+[r] + NADPH[r] + trans,cis-2,15-tetracosadienoyl-CoA[r] = (15Z)-tetracosenoyl-CoA[r] + NADP+[r]
ReversibleBalancedEC 2.3.1.199Fatty acid biosynthesisHuman-GEM MAR03617
H+[c] + malonyl-CoA[c] + palmitoleoyl-CoA[c] = CO2[c] + CoA[c] + 3-oxo-cis-9-octadecenoyl-CoA[c]
Left to rightBalancedEC 2.3.1.16Fatty acid biosynthesisHuman-GEM MAR03618
H+[r] + malonyl-CoA[r] + palmitoleoyl-CoA[r] = CO2[r] + CoA[r] + 3-oxo-cis-9-octadecenoyl-CoA[r]
Left to rightBalancedEC 2.3.1.16Fatty acid biosynthesisHuman-GEM MAR03619
H+[c] + NADPH[c] + 3-oxo-cis-9-octadecenoyl-CoA[c] = NADP+[c] + 3(S)-hydroxy-cis-9-octadecenoyl-CoA[c]
ReversibleBalancedEC 2.3.1.16Fatty acid biosynthesisHuman-GEM MAR03620
H+[r] + NADPH[r] + 3-oxo-cis-9-octadecenoyl-CoA[r] = NADP+[r] + 3(S)-hydroxy-cis-9-octadecenoyl-CoA[r]
ReversibleBalancedEC 4.2.1.17Fatty acid biosynthesisHuman-GEM MAR03621
cholesterol-ester plasma pool[r] = 0.0001 cholesterol-ester-10,13,16,19-docosa[r] + 0.0001 cholesterol-ester-10,13,16-docosa[r] + 0.0001 cholesterol-ester-10-hepta[r] + 0.0001 cholesterol-ester-11,14,17-eico[r] + 0.0001 cholesterol-ester-11,14-eicosa[r] + 0.0001 cholesterol-ester-11-docose[r] + 0.0001 cholesterol-ester-11-eico[r] + 0.0001 cholesterol-ester-12,15,18,21-tetracosa[r] + 0.0001 cholesterol-ester-13,16,19-doco[r] + 0.0001 cholesterol-ester-13,16-docosa[r] + 0.0001 cholesterol-ester-13-docose[r] + 0.0001 cholesterol-ester-13-eicose[r] + 0.0001 cholesterol-ester-13-octade[r] + 0.0001 cholesterol-ester-15-tetra[r] + 0.0041 cholesterol-ester-4,7,10,13,16,19-doco[r] + 0.0001 cholesterol-ester-4,7,10,13,16-docosa[r] + 0.0071 cholesterol-ester-5,8,11,14,17-eico[r] + 0.0001 cholesterol-ester-5,8,11-eico[r] + 0.0001 cholesterol-ester-5-tetra[r] + 0.0001 cholesterol-ester-6,9,12,15,18,21-tetra[r] + 0.0001 cholesterol-ester-6,9,12,15,18-tetraco[r] + 0.0001 cholesterol-ester-6,9,12,15-octa[r] + 0.0001 cholesterol-ester-6,9-octa[r] + 0.0001 cholesterol-ester-7,10,13,16,19-docosa[r] + 0.0001 cholesterol-ester-7,10,13,16-docosa[r] + 0.0406 cholesterol-ester-7-hexa[r] + 0.0001 cholesterol-ester-7-octade[r] + 0.0001 cholesterol-ester-7-tetrade[r] + 0.0001 cholesterol-ester-8,11,14,17-eico[r] + 0.0001 cholesterol-ester-8,11-eico[r] + 0.0001 cholesterol-ester-9,12,15,18,21-tetra[r] + 0.0001 cholesterol-ester-9,12,15,18-tetraco[r] + 0.0001 cholesterol-ester-9-eicose[r] + 0.0001 cholesterol-ester-9-heptade[r] + 0.0001 cholesterol-ester-9-octa[r] + 0.0001 cholesterol-ester-9-tetrade[r] + 0.0518 cholesterol-ester-arach[r] + 0.0001 cholesterol-ester-cis-vac[r] + 0.005 cholesterol-ester-dihomo-gamma[r] + 0.0001 cholesterol-ester-docosa[r] + 0.0001 cholesterol-ester-eico[r] + 0.0001 cholesterol-ester-gamma-lin[r] + 0.0001 cholesterol-ester-heneico[r] + 0.0001 cholesterol-ester-hepta[r] + 0.0001 cholesterol-ester-hexacosa[r] + 0.0001 cholesterol-ester-hexecose[r] + 0.0001 cholesterol-ester-laur[r] + 0.5254 cholesterol-ester-lin[r] + 0.0061 cholesterol-ester-linolen[r] + 0.0081 cholesterol-ester-myrist[r] + 0.0001 cholesterol-ester-nanode[r] + 0.1958 cholesterol-ester-ol[r] + 0.138 cholesterol-ester-palm[r] + 0.0001 cholesterol-ester-palmn[r] + 0.0001 cholesterol-ester-penta[r] + 0.0132 cholesterol-ester-stea[r] + 0.0001 cholesterol-ester-tetraco[r] + 0.0001 cholesterol-ester-trico[r] + 0.0001 cholesterol-ester-tridec[r]
ReversibleBalance undeterminableFormation and hydrolysis of cholesterol estersHuman-GEM MAR03622
3(S)-hydroxy-cis-9-octadecenoyl-CoA[c] = H2O[c] + trans,cis-2,9-octadecadienoyl-CoA[c]
ReversibleBalancedEC 4.2.1.17Fatty acid biosynthesisHuman-GEM MAR03623
3(S)-hydroxy-cis-9-octadecenoyl-CoA[r] = H2O[r] + trans,cis-2,9-octadecadienoyl-CoA[r]
ReversibleBalancedEC 4.2.1.17Fatty acid biosynthesisHuman-GEM MAR03624
cholesterol[r] + lauroyl-CoA[r] = cholesterol-ester-laur[r] + CoA[r]
Left to rightBalancedEC 2.3.1.26Formation and hydrolysis of cholesterol estersHuman-GEM MAR03625
cholesterol[r] + tridecanoyl-CoA[r] = cholesterol-ester-tridec[r] + CoA[r]
Left to rightBalancedEC 2.3.1.26Formation and hydrolysis of cholesterol estersHuman-GEM MAR03626
cholesterol[r] + myristoyl-CoA[r] = cholesterol-ester-myrist[r] + CoA[r]
Left to rightBalancedEC 2.3.1.26Formation and hydrolysis of cholesterol estersHuman-GEM MAR03627
(9E)-tetradecenoyl-CoA[r] + cholesterol[r] = cholesterol-ester-9-tetrade[r] + CoA[r]
Left to rightBalancedEC 2.3.1.26Formation and hydrolysis of cholesterol estersHuman-GEM MAR03628
(7Z)-tetradecenoyl-CoA[r] + cholesterol[r] = cholesterol-ester-7-tetrade[r] + CoA[r]
Left to rightBalancedEC 2.3.1.26Formation and hydrolysis of cholesterol estersHuman-GEM MAR03629
5-tetradecenoyl-CoA[r] + cholesterol[r] = cholesterol-ester-5-tetra[r] + CoA[r]
Left to rightBalancedEC 2.3.1.26Formation and hydrolysis of cholesterol estersHuman-GEM MAR03630
cholesterol[r] + pentadecanoyl-CoA[r] = cholesterol-ester-penta[r] + CoA[r]
Left to rightBalancedEC 2.3.1.26Formation and hydrolysis of cholesterol estersHuman-GEM MAR03631
cholesterol[r] + palmitoyl-CoA[r] = cholesterol-ester-palm[r] + CoA[r]
Left to rightBalancedEC 2.3.1.26Formation and hydrolysis of cholesterol estersHuman-GEM MAR03632