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Subsystem: Tyrosine metabolism Remove
1–50 of 78 reactions in Tyrosine metabolism
5,6-dihydroxyindole-2-carboxylate[c] = Melanin[c]
Left to rightBalancedEC 1.14.18.-Human-GEM MAR01816
3,3-diiodo-L-thyronine-4-O-sulfate[g] + H2O[g] = 3,3-diiodo-L-thyronine[g] + H+[g] + sulfate[g]
ReversibleBalancedEC 3.1.6.2Human-GEM MAR02536
3,3-diiodo-L-thyronine-4-O-sulfate[r] + H2O[r] = 3,3-diiodo-L-thyronine[r] + H+[r] + sulfate[r]
ReversibleBalancedEC 3.1.6.2Human-GEM MAR02538
3,5-diiodo-L-thyronine-4-O-sulfate[g] + H2O[g] = 3,5-diiodo-L-thyronine[g] + H+[g] + sulfate[g]
ReversibleBalancedEC 3.1.6.2Human-GEM MAR02539
3,5-diiodo-L-thyronine-4-O-sulfate[r] + H2O[r] = 3,5-diiodo-L-thyronine[r] + H+[r] + sulfate[r]
ReversibleBalancedEC 3.1.6.2Human-GEM MAR02589
3-monoiodo-L-thyronine-4-O-sulfate[g] + H2O[g] = 3-monoiodo-L-thyronine[g] + H+[g] + sulfate[g]
ReversibleBalancedEC 3.1.6.2Human-GEM MAR02595
3-monoiodo-L-thyronine-4-O-sulfate[r] + H2O[r] = 3-monoiodo-L-thyronine[r] + H+[r] + sulfate[r]
ReversibleBalancedEC 3.1.6.2Human-GEM MAR02597
UDP-glucuronate[c] + 3,5,3,5-Tetraiodothyroacetate[c] = H+[c] + UDP[c] + 3,5,3,5-Tetraiodothyroacetate-Beta-D-Glucuronoside[c]
Left to rightBalancedEC 2.4.1.17Human-GEM MAR02615
UDP-glucuronate[r] + 3,5,3,5-Tetraiodothyroacetate[r] = H+[r] + UDP[r] + 3,5,3,5-Tetraiodothyroacetate-Beta-D-Glucuronoside[r]
Left to rightBalancedEC 2.4.1.17Human-GEM MAR02617
UDP-glucuronate[c] + 3,3,5-Triiodothyroacetate[c] = H+[c] + UDP[c] + 3,3,5-Triiodothyroacetate-Beta-D-Glucuronoside[c]
Left to rightBalancedEC 2.4.1.17Human-GEM MAR02619
UDP-glucuronate[r] + 3,3,5-Triiodothyroacetate[r] = H+[r] + UDP[r] + 3,3,5-Triiodothyroacetate-Beta-D-Glucuronoside[r]
Left to rightBalancedEC 2.4.1.17Human-GEM MAR02627
UDP-glucuronate[c] + 3,5,3-Triiodothyroacetate[c] = H+[c] + UDP[c] + 3,5,3-Triiodothyroacetate-Beta-D-Glucuronoside[c]
Left to rightBalancedEC 2.4.1.17Human-GEM MAR02628
UDP-glucuronate[r] + 3,5,3-Triiodothyroacetate[r] = H+[r] + UDP[r] + 3,5,3-Triiodothyroacetate-Beta-D-Glucuronoside[r]
Left to rightBalancedEC 2.4.1.17Human-GEM MAR02631
UDP-glucuronate[c] + 3,5-Diiodothyroacetate[c] = H+[c] + UDP[c] + 3,5-Diiodothyroacetate-Beta-D-Glucuronoside[c]
Left to rightBalancedEC 2.4.1.17Human-GEM MAR02632
UDP-glucuronate[r] + 3,5-Diiodothyroacetate[r] = H+[r] + UDP[r] + 3,5-Diiodothyroacetate-Beta-D-Glucuronoside[r]
Left to rightBalancedEC 2.4.1.17Human-GEM MAR02637
GSH[x] + L-dopaquinone[x] = 5-S-glutathionyl-L-dopa[x]
ReversibleBalancedEC 2.5.1.18Human-GEM MAR02995
dopamine-O-quinone[x] + GSH[x] = 5-S-glutathionyl-dopamine[x]
ReversibleBalancedEC 2.5.1.18Human-GEM MAR03046
adrenochrome[x] + GSH[x] = 5-S-glutathionyl-adrenochrome hydroquinone[x]
ReversibleBalancedEC 2.5.1.18Human-GEM MAR03154
GSH[x] + noradrenochrome[x] = 5-S-glutathionyl-noradrenochrome hydroquinone[x]
ReversibleBalancedEC 2.5.1.18Human-GEM MAR03155
GSH[x] + L-dopachrome[x] = 5-S-glutathionyl-dopachrome hydroquinone[x]
ReversibleBalancedEC 2.5.1.18Human-GEM MAR03159
dopaminochrome[x] + GSH[x] = 5-S-glutathionyl-aminochrome reduced[x]
ReversibleBalancedEC 2.5.1.18Human-GEM MAR03161
dopamine[l] + H2O2[l] = dopamine-O-quinone[l] + 2 H2O[l]
Left to rightBalancedEC 1.11.1.7Human-GEM MAR03391
dopamine[x] + H2O2[x] = dopamine-O-quinone[x] + 2 H2O[x]
Left to rightBalancedEC 1.11.1.7Human-GEM MAR03392
H+[c] + L-dopachrome[c] + NADH[c] = 2-carboxy-2,3-dihydro-5,6-dihydroxyindole[c] + NAD+[c]
ReversibleBalancedHuman-GEM MAR03599
hordenine[g] + O2[g] = H2O[g] + N,N-dimethyldopaminequinone[g]
Left to rightBalancedEC 1.14.18.1Human-GEM MAR03613
hordenine[l] + O2[l] = H2O[l] + N,N-dimethyldopaminequinone[l]
Left to rightBalancedEC 1.14.18.1Human-GEM MAR03614
formaldehyde[c] + GSH[c] = hydroxymethylglutathione[c]
ReversibleBalancedEC 4.4.1.22Human-GEM MAR03935
noradrenaline[r] = 5 H+[r] + noradrenochrome[r]
Left to rightUnbalancedEC 2.1.1.13Human-GEM MAR04015
H+[c] + phenylalanine[c] = CO2[c] + phenethylamine[c]
Left to rightBalancedEC 4.1.1.28Human-GEM MAR04681
H2O[c] + O2[c] + phenethylamine[c] = H+[c] + H2O2[c] + NH3[c] + phenylacetaldehyde[c]
Left to rightBalancedEC 1.4.3.4, 1.4.3.21Human-GEM MAR04682
H2O[c] + NAD+[c] + phenylacetaldehyde[c] = 2 H+[c] + NADH[c] + phenylacetate[c]
Left to rightBalancedEC 1.2.1.5, 1.2.1.39Human-GEM MAR04683
H2O[m] + NAD+[m] + phenylacetaldehyde[m] = 2 H+[m] + NADH[m] + phenylacetate[m]
Left to rightBalancedEC 1.2.1.5, 1.2.1.39Human-GEM MAR04685
2 H+[c] + NADPH[c] + phenylacetate[c] = H2O[c] + NADP+[c] + phenylacetaldehyde[c]
ReversibleBalancedEC 1.2.1.5Human-GEM MAR04686
2 H+[m] + NADPH[m] + phenylacetate[m] = H2O[m] + NADP+[m] + phenylacetaldehyde[m]
ReversibleBalancedEC 1.2.1.5Human-GEM MAR04687
homogentisate[c] + NADPH[c] + O2[c] = CO2[c] + gentisate aldehyde[c] + H2O[c] + NADP+[c]
Left to rightUnbalancedEC 4.1.1.-Human-GEM MAR04702
gentisate aldehyde[c] + H2O[c] + NAD+[c] = 2,5-dihydroxybenzoate[c] + 2 H+[c] + NADH[c]
Left to rightBalancedEC 1.2.1.29Human-GEM MAR04703
gentisate aldehyde[c] + H2O[c] + O2[c] = 2,5-dihydroxybenzoate[c] + H+[c] + H2O2[c]
Left to rightBalancedEC 1.2.3.1Human-GEM MAR04704
2 H+[c] + H2O2[c] + 2 iodide[c] = 2 H2O[c] + iodine[c]
Left to rightBalancedEC 1.11.1.8Human-GEM MAR06988
dopamine[c] + PAPS[c] = dopamine-3-O-sulfate[c] + H+[c] + PAP[c]
Left to rightBalancedEC 2.8.2.1Human-GEM MAR07689
H+[c] + NADPH[c] + O2[c] = H2O2[c] + NADP+[c]
Left to rightBalancedEC 1.11.1.-, 1.6.3.1Human-GEM MAR07701
noradrenaline[c] + PAPS[c] = H+[c] + norepinephrine sulfate[c] + PAP[c]
Left to rightBalancedEC 2.8.2.1Human-GEM MAR08094
H2O[c] + methylamine[c] + O2[c] = formaldehyde[c] + H+[c] + H2O2[c] + NH3[c]
Left to rightBalancedEC 1.4.3.21, 1.4.3.22Human-GEM MAR08529
formaldehyde[c] + GSH[c] + NAD+[c] = formylglutathione[c] + H+[c] + NADH[c]
ReversibleBalancedEC 1.1.1.1Human-GEM MAR08530
2 2-carboxy-2,3-dihydro-5,6-dihydroxyindole[c] + O2[c] = 2 H2O[c] + 2 L-dopachrome[c]
Left to rightBalancedEC 1.14.18.1Human-GEM MAR08533
PAPS[c] + triiodothyronine[c] = 3,5,3-triiodothyronine-4-sulfate[c] + H+[c] + PAP[c]
Left to rightBalancedEC 2.8.2.1Human-GEM MAR08534
PAPS[c] + tyramine[c] = H+[c] + PAP[c] + tyramine-O-sulfate[c]
Left to rightBalancedEC 2.8.2.1Human-GEM MAR08535
O2[c] + tetrahydrobiopterin[c] + tyrosine[c] = 4alpha-hydroxytetrahydrobiopterin[c] + L-dopa[c]
Left to rightBalancedEC 1.14.16.2Human-GEM MAR08537
5,6-dihydroxyindole-2-carboxylate[c] + O2[c] + indole-5,6-quinone[c] = H2O[c] + eumelanin[c]
Left to rightBalancedHuman-GEM MAR08540
O2[c] + 2 tyrosine[c] = 2 L-dopa[c]
Left to rightBalancedEC 1.14.18.1Human-GEM MAR08541
2 L-dopa[c] + O2[c] = 2 H2O[c] + 2 L-dopaquinone[c]
Left to rightBalancedEC 1.14.18.1Human-GEM MAR08542