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3,301–3,350 of 12,877 reactions from Human-GEM
H2O[m] + trans-2-cis-8-tetradecadienoyl-CoA[m] = (3S)-3-hydroxy-cis-8-tetradecenoyl-CoA[m]
ReversibleBalancedEC 4.2.1.17Fatty acid oxidationHuman-GEM MAR03379
NAD+[m] + (3S)-3-hydroxy-cis-8-tetradecenoyl-CoA[m] = H+[m] + NADH[m] + 3-oxo-cis-8-tetradecenoyl-CoA[m]
ReversibleBalancedEC 1.1.1.35Fatty acid oxidationHuman-GEM MAR03380
CoA[m] + 3-oxo-cis-8-tetradecenoyl-CoA[m] = acetyl-CoA[m] + cis-6-dodecenoyl-CoA[m]
ReversibleBalancedEC 2.3.1.16Fatty acid oxidationHuman-GEM MAR03381
acetyl-CoA[c] + 1-Alkyl-Sn-Glycerol 3-Phosphate[c] = CoA[c] + 1-Alkyl-2-Acetyl-Sn-Glycerol 3-Phosphate[c]
ReversibleBalance undeterminableGlycerophospholipid metabolismHuman-GEM MAR03382
H2O[c] + 1-Alkyl-2-Acetyl-Sn-Glycerol 3-Phosphate[c] = 1-alkyl-2-acetyl-sn-glycerol[c] + Pi[c]
ReversibleBalance undeterminableEC 3.1.3.59Glycerophospholipid metabolismHuman-GEM MAR03383
AKG[x] + O2[x] + 3(S)-phytanoyl-CoA[x] = CO2[x] + succinate[x] + 3(S)-2-hydroxyphytanoyl-CoA[x]
Left to rightBalancedEC 1.14.11.18Fatty acid oxidationHuman-GEM MAR03384
3(S)-2-hydroxyphytanoyl-CoA[x] = 2(S)-pristanal[x] + formyl-CoA[x]
ReversibleBalancedEC 1.2.1.3Fatty acid oxidationHuman-GEM MAR03385
2(S)-pristanal[x] + H2O[x] + NAD+[x] = 2 H+[x] + NADH[x] + (2S)-pristanic acid[x]
ReversibleBalancedEC 1.2.1.48Fatty acid oxidationHuman-GEM MAR03386
ATP[x] + CoA[x] + (2S)-pristanic acid[x] = (2S)-pristanoyl-CoA[x] + AMP[x] + PPi[x]
Left to rightBalancedEC 6.2.1.3Fatty acid oxidationHuman-GEM MAR03387
ATP[c] + CoA[c] + (3S)-phytanic acid[c] = AMP[c] + PPi[c] + 3(S)-phytanoyl-CoA[c]
Left to rightBalancedEC 6.2.1.24Fatty acid oxidationHuman-GEM MAR03388
ATP[x] + CoA[x] + (3S)-phytanic acid[x] = AMP[x] + PPi[x] + 3(S)-phytanoyl-CoA[x]
Left to rightBalancedEC 6.2.1.24Fatty acid oxidationHuman-GEM MAR03389
(2R)-pristanic acid[c] + ATP[c] + CoA[c] = (2R)-pristanoyl-CoA[c] + AMP[c] + PPi[c]
Left to rightBalancedEC 1.14.14.94Fatty acid oxidationHuman-GEM MAR03390
dopamine[l] + H2O2[l] = dopamine-O-quinone[l] + 2 H2O[l]
Left to rightBalancedEC 1.11.1.7Tyrosine metabolismHuman-GEM MAR03391
dopamine[x] + H2O2[x] = dopamine-O-quinone[x] + 2 H2O[x]
Left to rightBalancedEC 1.11.1.7Tyrosine metabolismHuman-GEM MAR03392
gamma-linolenoyl-CoA[r] + H+[r] + malonyl-CoA[r] = 3-oxo-dihomo-gamma-linolenoyl-CoA[r] + CO2[r] + CoA[r]
Left to rightBalancedEC 3.3.2.9Fatty acid oxidationHuman-GEM MAR03393
H+[r] + NADPH[r] + trans-2-cis,cis,cis-8,11,14-eicosatetraenoyl-CoA[r] = dihomo-gamma-linolenoyl-CoA[r] + NADP+[r]
ReversibleBalancedEC 3.3.2.9Fatty acid oxidationHuman-GEM MAR03394
eicosa-(2E,8Z,11Z,14Z,17Z)-pentaenoyl-CoA[r] + H+[r] + NADPH[r] = (8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA[r] + NADP+[r]
ReversibleBalancedEC 2.3.1.199Fatty acid oxidationHuman-GEM MAR03395
(10Z)-heptadecenoyl-CoA[m] + 7 CoA[m] + 6 FAD[m] + 7 H2O[m] + 7 NAD+[m] = 7 acetyl-CoA[m] + 6 FADH2[m] + 7 H+[m] + 7 NADH[m] + propanoyl-CoA[m]
Left to rightBalancedBeta oxidation of odd-chain fatty acids (mitochondrial)Human-GEM MAR03396
9-heptadecenoyl-CoA[m] + 7 CoA[m] + 6 FAD[m] + 7 H2O[m] + 7 NAD+[m] = 7 acetyl-CoA[m] + 6 FADH2[m] + 7 H+[m] + 7 NADH[m] + propanoyl-CoA[m]
Left to rightBalancedBeta oxidation of odd-chain fatty acids (mitochondrial)Human-GEM MAR03397
(9E)-tetradecenoyl-CoA[m] + 6 CoA[m] + 5 FAD[m] + 6 H2O[m] + 6 NAD+[m] = 7 acetyl-CoA[m] + 5 FADH2[m] + 6 H+[m] + 6 NADH[m]
Left to rightBalancedEC 4.2.1.17, 1.1.1.35, 1.1.1.211, 1.3.8.7, 1.3.8.8, 1.3.8.9, 2.3.1.16Beta oxidation of even-chain fatty acids (mitochondrial)Human-GEM MAR03398
(6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoA[r] + H+[r] + malonyl-CoA[r] = 3-keto-eicosa-8,11,14,17-all-cis-tetraenoyl-CoA[r] + CO2[r] + CoA[r]
Left to rightBalancedEC 3.3.2.9Fatty acid oxidationHuman-GEM MAR03399
androstenediol[m] + H+[m] + NAD+[m] = 5-alpha-dihydrotestosterone[m] + NADH[m]
ReversibleUnbalancedEC 1.1.1.145Androgen metabolismHuman-GEM MAR03400
3-keto-eicosa-8,11,14,17-all-cis-tetraenoyl-CoA[r] + H+[r] + NADPH[r] = 3(S)-hydroxy-all-cis-8,11,14,17-eicosatetraenoyl-CoA[r] + NADP+[r]
ReversibleBalancedEC 3.1.3.59Fatty acid oxidationHuman-GEM MAR03401
3(S)-hydroxy-all-cis-8,11,14,17-eicosatetraenoyl-CoA[r] = eicosa-(2E,8Z,11Z,14Z,17Z)-pentaenoyl-CoA[r] + H2O[r]
ReversibleBalancedEC 2.3.1.199Fatty acid oxidationHuman-GEM MAR03402
2-trans-7,10,13,16,19-all-cis-docosahexaenoyl-CoA[r] + H+[r] + NADPH[r] = (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA[r] + NADP+[r]
ReversibleBalancedEC 1.14.11.18Fatty acid oxidationHuman-GEM MAR03403
(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA[r] + H+[r] + malonyl-CoA[r] = 3-oxo-docosa-7,10,13,16,19-all-cis-pentaenoyl-CoA[r] + CO2[r] + CoA[r]
Left to rightBalancedEC 1.2.1.48Fatty acid oxidationHuman-GEM MAR03404
3-oxo-docosa-7,10,13,16,19-all-cis-pentaenoyl-CoA[r] + H+[r] + NADPH[r] = 3(S)-hydroxy-docosa-7,10,13,16,19-all-cis-pentaenoyl-CoA[r] + NADP+[r]
ReversibleBalancedEC 6.2.1.24Fatty acid oxidationHuman-GEM MAR03405
(13Z)-octadecenoyl-CoA[m] + 8 CoA[m] + 7 FAD[m] + 8 H2O[m] + 8 NAD+[m] = 9 acetyl-CoA[m] + 7 FADH2[m] + 8 H+[m] + 8 NADH[m]
Left to rightBalancedEC 4.2.1.17, 1.1.1.35, 1.1.1.211, 1.3.8.7, 1.3.8.8, 1.3.8.9, 2.3.1.16Beta oxidation of even-chain fatty acids (mitochondrial)Human-GEM MAR03406
(9E)-octadecenoyl-CoA[m] + 8 CoA[m] + 7 FAD[m] + 8 H2O[m] + 8 NAD+[m] = 9 acetyl-CoA[m] + 7 FADH2[m] + 8 H+[m] + 8 NADH[m]
Left to rightBalancedEC 4.2.1.17, 1.1.1.35, 1.1.1.211, 1.3.8.7, 1.3.8.8, 1.3.8.9, 2.3.1.16Beta oxidation of even-chain fatty acids (mitochondrial)Human-GEM MAR03407
(7Z)-octadecenoyl-CoA[m] + 8 CoA[m] + 7 FAD[m] + 8 H2O[m] + 8 NAD+[m] = 9 acetyl-CoA[m] + 7 FADH2[m] + 8 H+[m] + 8 NADH[m]
Left to rightBalancedEC 4.2.1.17, 1.1.1.35, 1.1.1.211, 1.3.8.7, 1.3.8.8, 1.3.8.9, 2.3.1.16Beta oxidation of even-chain fatty acids (mitochondrial)Human-GEM MAR03408
(6Z,9Z)-octadecadienoyl-CoA[m] + 8 CoA[m] + 6 FAD[m] + 8 H2O[m] + 8 NAD+[m] = 9 acetyl-CoA[m] + 6 FADH2[m] + 8 H+[m] + 8 NADH[m]
Left to rightBalancedEC 4.2.1.17, 1.1.1.35, 1.1.1.211, 1.3.8.7, 1.3.8.8, 1.3.8.9, 2.3.1.16Beta oxidation of even-chain fatty acids (mitochondrial)Human-GEM MAR03409
3(S)-hydroxy-docosa-7,10,13,16,19-all-cis-pentaenoyl-CoA[r] = 2-trans-7,10,13,16,19-all-cis-docosahexaenoyl-CoA[r] + H2O[r]
ReversibleBalancedEC 1.2.1.48Fatty acid oxidationHuman-GEM MAR03410
9-eicosenoyl-CoA[m] + 9 CoA[m] + 8 FAD[m] + 9 H2O[m] + 9 NAD+[m] = 10 acetyl-CoA[m] + 8 FADH2[m] + 9 H+[m] + 9 NADH[m]
Left to rightBalancedEC 4.2.1.17, 1.1.1.35, 1.1.1.211, 1.3.8.7, 1.3.8.8, 1.3.8.9, 2.3.1.16Beta oxidation of even-chain fatty acids (mitochondrial)Human-GEM MAR03411
2-trans-9,12,15,18,21-all-cis-tetracosahexaenoyl-CoA[r] + H+[r] + NADPH[r] = NADP+[r] + tetracosa-9,12,15,18,21-all-cis-pentaenoyl-CoA[r]
ReversibleBalancedEC 2.3.1.199Fatty acid oxidationHuman-GEM MAR03412
(8Z,11Z)-eicosadienoyl-CoA[m] + 9 CoA[m] + 7 FAD[m] + 9 H2O[m] + 9 NAD+[m] = 10 acetyl-CoA[m] + 7 FADH2[m] + 9 H+[m] + 9 NADH[m]
Left to rightBalancedEC 4.2.1.17, 1.1.1.35, 1.1.1.211, 1.3.8.7, 1.3.8.8, 1.3.8.9, 2.3.1.16Beta oxidation of even-chain fatty acids (mitochondrial)Human-GEM MAR03413
(5Z,8Z,11Z)-eicosatrienoyl-CoA[m] + 9 CoA[m] + 6 FAD[m] + 9 H2O[m] + 9 NAD+[m] = 10 acetyl-CoA[m] + 6 FADH2[m] + 9 H+[m] + 9 NADH[m]
Left to rightBalancedEC 4.2.1.17, 1.1.1.35, 1.1.1.211, 1.3.8.7, 1.3.8.8, 1.3.8.9, 2.3.1.16Beta oxidation of even-chain fatty acids (mitochondrial)Human-GEM MAR03414
(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA[r] + H+[r] + malonyl-CoA[r] = 3-oxo-all-cis-6,9,12,15,18-tetracosapentaenoyl-CoA[r] + CO2[r] + CoA[r]
Left to rightBalancedEC 1.1.1.35Fatty acid oxidationHuman-GEM MAR03415
(11Z)-docosenoyl-CoA[m] + 10 CoA[m] + 9 FAD[m] + 10 H2O[m] + 10 NAD+[m] = 11 acetyl-CoA[m] + 9 FADH2[m] + 10 H+[m] + 10 NADH[m]
Left to rightBalancedEC 4.2.1.17, 1.1.1.35, 1.1.1.211, 1.3.8.7, 1.3.8.8, 1.3.8.9, 2.3.1.16Beta oxidation of even-chain fatty acids (mitochondrial)Human-GEM MAR03416
3-oxo-all-cis-6,9,12,15,18-tetracosapentaenoyl-CoA[r] + H+[r] + NADPH[r] = 3(S)-hydroxy-tetracosa-9,12,15,18,21-all-cis-pentaenoyl-CoA[r] + NADP+[r]
ReversibleBalancedEC 1.3.3.6Fatty acid oxidationHuman-GEM MAR03417
3(S)-hydroxy-tetracosa-9,12,15,18,21-all-cis-pentaenoyl-CoA[r] = 2-trans-9,12,15,18,21-all-cis-tetracosahexaenoyl-CoA[r] + H2O[r]
ReversibleBalancedEC 4.2.1.17Fatty acid oxidationHuman-GEM MAR03418
desmosterol[n] + H+[n] + NADPH[n] = cholesterol[n] + NADP+[n]
ReversibleBalancedEC 1.1.1.35Cholesterol metabolismHuman-GEM MAR03419
H+[c] + NADPH[c] + 4,4-Dimethylcholesta-8(9),14-Dien-3Beta-Ol[c] = 4,4-dimethyl-5alpha-cholesta-8-en-3-beta-ol[c] + NADP+[c]
ReversibleBalancedEC 1.3.1.70Cholesterol metabolismHuman-GEM MAR03420
(7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA[m] + 10 CoA[m] + 6 FAD[m] + 10 H2O[m] + 10 NAD+[m] = 11 acetyl-CoA[m] + 6 FADH2[m] + 10 H+[m] + 10 NADH[m]
Left to rightBalancedEC 4.2.1.17, 1.1.1.35, 1.1.1.211, 1.3.8.7, 1.3.8.8, 1.3.8.9, 2.3.1.16Beta oxidation of even-chain fatty acids (mitochondrial)Human-GEM MAR03421
(11Z,14Z)-eicosadienoyl-CoA[m] + 9 CoA[m] + 7 FAD[m] + 9 H2O[m] + 9 NAD+[m] = 10 acetyl-CoA[m] + 7 FADH2[m] + 9 H+[m] + 9 NADH[m]
Left to rightBalancedEC 4.2.1.17, 1.1.1.35, 1.1.1.211, 1.3.8.7, 1.3.8.8, 1.3.8.9, 2.3.1.16Beta oxidation of even-chain fatty acids (mitochondrial)Human-GEM MAR03423
(13Z,16Z)-docosadienoyl-CoA[m] + 10 CoA[m] + 8 FAD[m] + 10 H2O[m] + 10 NAD+[m] = 11 acetyl-CoA[m] + 8 FADH2[m] + 10 H+[m] + 10 NADH[m]
Left to rightBalancedEC 4.2.1.17, 1.1.1.35, 1.1.1.211, 1.3.8.7, 1.3.8.8, 1.3.8.9, 2.3.1.16Beta oxidation of even-chain fatty acids (mitochondrial)Human-GEM MAR03424
10,13,16-docosatrienoyl-CoA[m] + 10 CoA[m] + 7 FAD[m] + 10 H2O[m] + 10 NAD+[m] = 11 acetyl-CoA[m] + 7 FADH2[m] + 10 H+[m] + 10 NADH[m]
Left to rightBalancedEC 4.2.1.17, 1.1.1.35, 1.1.1.211, 1.3.8.7, 1.3.8.8, 1.3.8.9, 2.3.1.16Beta oxidation of even-chain fatty acids (mitochondrial)Human-GEM MAR03425
(8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA[m] + 9 CoA[m] + 5 FAD[m] + 9 H2O[m] + 9 NAD+[m] = 10 acetyl-CoA[m] + 5 FADH2[m] + 9 H+[m] + 9 NADH[m]
Left to rightBalancedEC 4.2.1.17, 1.1.1.35, 1.1.1.211, 1.3.8.7, 1.3.8.8, 1.3.8.9, 2.3.1.16Beta oxidation of even-chain fatty acids (mitochondrial)Human-GEM MAR03427
(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA[m] + 9 CoA[m] + 4 FAD[m] + 9 H2O[m] + 9 NAD+[m] = 10 acetyl-CoA[m] + 4 FADH2[m] + 9 H+[m] + 9 NADH[m]
Left to rightBalancedEC 4.2.1.17, 1.1.1.35, 1.1.1.211, 1.3.8.7, 1.3.8.8, 1.3.8.9, 2.3.1.16Beta oxidation of even-chain fatty acids (mitochondrial)Human-GEM MAR03428
(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA[m] + 10 CoA[m] + 5 FAD[m] + 10 H2O[m] + 10 NAD+[m] = 11 acetyl-CoA[m] + 5 FADH2[m] + 10 H+[m] + 10 NADH[m]
Left to rightBalancedEC 4.2.1.17, 1.1.1.35, 1.1.1.211, 1.3.8.7, 1.3.8.8, 1.3.8.9, 2.3.1.16Beta oxidation of even-chain fatty acids (mitochondrial)Human-GEM MAR03429
(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA[m] + 10 CoA[m] + 4 FAD[m] + 10 H2O[m] + 10 NAD+[m] = 11 acetyl-CoA[m] + 4 FADH2[m] + 10 H+[m] + 10 NADH[m]
Left to rightBalancedEC 4.2.1.17, 1.1.1.35, 1.1.1.211, 1.3.8.7, 1.3.8.8, 1.3.8.9, 2.3.1.16Beta oxidation of even-chain fatty acids (mitochondrial)Human-GEM MAR03430