Skip to content

Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

Atlas Graph Twin Access

Search the graph

Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

Atlas Graph Twin Access

Loading the page.

Catalyst

Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

The graph

Compounds
Outcomes
Proteins
Atlas
Interactions
Papers
Articles
Graph
Search

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases
Reactions
Reach

How it works

Mission
Method
Twin
How to read the evidence
Sources and licences

Build on it

Access
In your assistant
For agents
Query the graph
Bulk export

A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

27,851–27,900 of 31,435, by identifier

formate(in) + chloride(out) = formate(out) + chloride(in)
Direction not assertedBalancedTransportRhea 72267
oxalate(in) + formate(out) = oxalate(out) + formate(in)
Direction not assertedBalancedTransportRhea 72271
oxalate(in) + sulfate(out) = oxalate(out) + sulfate(in)
Direction not assertedBalancedTransportRhea 72275
5-carboxymethylaminomethyl-2-thiouridine(34) in tRNA + A + H2O = 5-aminomethyl-2-thiouridine(34) in tRNA + glyoxylate + AH2
Direction not assertedBalancedRhea 72279
a methoxylated aromatic compound + Co(I)-[methoxylated-aromatic-compound-specific corrinoid protein] + H(+) = a phenol + methyl-Co(III)-[methoxylated-aromatic-compound-specific corrinoid protein]
Direction not assertedBalance undeterminableRhea 72283
2,2-dimethylsuccinate(out) + 3 Na(+)(out) = 2,2-dimethylsuccinate(in) + 3 Na(+)(in)
Direction not asserted

Balanced

Transport

Rhea 72287

2,3-dimethylsuccinate(out) + 3 Na(+)(out) = 2,3-dimethylsuccinate(in) + 3 Na(+)(in)

Direction not assertedBalancedTransportRhea 72291

malate(out) + 3 Na(+)(out) = malate(in) + 3 Na(+)(in)

Direction not assertedBalancedTransportRhea 72295

3,3',5-triiodo-L-thyronine(out) + L-glutamate(in) = 3,3',5-triiodo-L-thyronine(in) + L-glutamate(out)

Left to rightBalancedTransportRhea 72299

L-thyroxine(out) + L-glutamate(in) = L-thyroxine(in) + L-glutamate(out)

Left to rightBalancedTransportRhea 72303

taurocholate(out) + L-glutamate(in) = taurocholate(in) + L-glutamate(out)

Left to rightBalancedTransportRhea 72307

taurocholate(out) + glutathione(in) = taurocholate(in) + glutathione(out)

Direction not assertedBalancedTransportRhea 72311

leukotriene C4(out) + glutathione(in) = leukotriene C4(in) + glutathione(out)

Direction not assertedBalancedTransportRhea 72315

urate(out) + n chloride(in) = urate(in) + n chloride(out)

Direction not assertedBalance undeterminableTransportRhea 72319

thiosulfate(out) + 3 Na(+)(out) = thiosulfate(in) + 3 Na(+)(in)

Direction not assertedBalancedTransportRhea 72323

Co(I)-[methoxylated-aromatic-compound-specific corrinoid protein] + vanillate + H(+) = methyl-Co(III)-[methoxylated-aromatic-compound-specific corrinoid protein] + 3,4-dihydroxybenzoate

Direction not assertedBalance undeterminableRhea 72327

3-hydroxy-4-methoxybenzoate + Co(I)-[methoxylated-aromatic-compound-specific corrinoid protein] + H(+) = methyl-Co(III)-[methoxylated-aromatic-compound-specific corrinoid protein] + 3,4-dihydroxybenzoate

Direction not assertedBalance undeterminableRhea 72331

syringate + Co(I)-[methoxylated-aromatic-compound-specific corrinoid protein] + H(+) = 3-O-methylgallate + methyl-Co(III)-[methoxylated-aromatic-compound-specific corrinoid protein]

Direction not assertedBalance undeterminableRhea 72335

guaiacol + Co(I)-[methoxylated-aromatic-compound-specific corrinoid protein] + H(+) = methyl-Co(III)-[methoxylated-aromatic-compound-specific corrinoid protein] + catechol

Direction not assertedBalance undeterminableRhea 72339

3-methoxyphenol + Co(I)-[methoxylated-aromatic-compound-specific corrinoid protein] + H(+) = resorcinol + methyl-Co(III)-[methoxylated-aromatic-compound-specific corrinoid protein]

Direction not assertedBalance undeterminableRhea 72343

veratrole + Co(I)-[methoxylated-aromatic-compound-specific corrinoid protein] + H(+) = 3-methoxyphenol + methyl-Co(III)-[methoxylated-aromatic-compound-specific corrinoid protein]

Direction not assertedBalance undeterminableRhea 72347

glycocholate(out) + glutarate(in) = glycocholate(in) + glutarate(out)

Direction not assertedBalancedTransportRhea 72351

dehydroepiandrosterone 3-sulfate(out) + glutarate(in) = dehydroepiandrosterone 3-sulfate(in) + glutarate(out)

Direction not assertedBalancedTransportRhea 72355

glutarate(in) + succinate(out) = glutarate(out) + succinate(in)

Direction not assertedBalancedTransportRhea 72359

hydrogencarbonate(in) + chloride(out) = hydrogencarbonate(out) + chloride(in)

Direction not assertedBalancedTransportRhea 72363

estrone 3-sulfate(out) + succinate(in) = estrone 3-sulfate(in) + succinate(out)

Direction not assertedBalancedTransportRhea 72367

dehydroepiandrosterone 3-sulfate(out) + succinate(in) = dehydroepiandrosterone 3-sulfate(in) + succinate(out)

Direction not assertedBalancedTransportRhea 72371

iodide(in) + hydrogencarbonate(out) = iodide(out) + hydrogencarbonate(in)

Direction not assertedBalancedTransportRhea 72375

iodide(in) + chloride(out) = iodide(out) + chloride(in)

Direction not assertedBalancedTransportRhea 72379

urate(in) + Na(+)(out) = urate(out) + Na(+)(in)

Direction not assertedBalancedTransportRhea 72383

2 hydrogencarbonate(out) + sulfate(in) = 2 hydrogencarbonate(in) + sulfate(out)

Direction not assertedBalancedTransportRhea 72387

oxalate(in) + 2 hydrogencarbonate(out) = oxalate(out) + 2 hydrogencarbonate(in)

Direction not assertedBalancedTransportRhea 72391

K(+)(out) + 2 chloride(out) + Na(+)(out) = K(+)(in) + 2 chloride(in) + Na(+)(in)

Left to rightBalancedTransportRhea 72395

estrone 3-sulfate(in) + 2-oxoglutarate(out) = estrone 3-sulfate(out) + 2-oxoglutarate(in)

Direction not assertedBalancedTransportRhea 72399

urate(in) + 2-oxoglutarate(out) = urate(out) + 2-oxoglutarate(in)

Direction not assertedBalancedTransportRhea 72403

Li(+)(out) + H(+)(in) = Li(+)(in) + H(+)(out)

Direction not assertedBalancedTransportRhea 72407

inulobiose = alpha-D-fructofuranose-beta-D-fructofuranose 2',1:2,3'-dianhydride + H2O

Direction not assertedBalancedRhea 72411

Li(+)(in) + Na(+)(out) = Li(+)(out) + Na(+)(in)

Direction not assertedBalancedTransportRhea 72415

(E)-4-coumarate + ATP + H(+) = (E)-4-coumaroyl-AMP + diphosphate

Direction not assertedBalancedRhea 72419

(E)-4-coumaroyl-AMP + CoA = (E)-4-coumaroyl-CoA + AMP + H(+)

Direction not assertedBalancedRhea 72423

K(+)(in) + chloride(in) = K(+)(out) + chloride(out)

Direction not assertedBalancedTransportRhea 72427

(E)-caffeate + ATP + H(+) = (E)-caffeoyl-AMP + diphosphate

Direction not assertedBalancedRhea 72431

(E)-caffeoyl-AMP + CoA = (E)-caffeoyl-CoA + AMP + H(+)

Direction not assertedBalancedRhea 72435

(E)-ferulate + ATP + H(+) = (E)-feruloyl-AMP + diphosphate

Direction not assertedBalancedRhea 72439

(E)-feruloyl-AMP + CoA = (E)-feruloyl-CoA + AMP + H(+)

Direction not assertedBalancedRhea 72443

estrone 3-sulfate(out) + a dicarboxylate(in) = estrone 3-sulfate(in) + a dicarboxylate(out)

Direction not assertedBalance undeterminableTransportRhea 72447

dehydroepiandrosterone 3-sulfate(out) + a dicarboxylate(in) = dehydroepiandrosterone 3-sulfate(in) + a dicarboxylate(out)

Direction not assertedBalance undeterminableTransportRhea 72451

fumarate(out) + 3 H(+)(out) = fumarate(in) + 3 H(+)(in)

Direction not assertedBalancedTransportRhea 72455

fumarate(in) + L-aspartate(out) = fumarate(out) + L-aspartate(in)

Direction not assertedBalancedTransportRhea 72459

L-threonyl-[protein] + NAD(+) = O-(ADP-D-ribosyl)-L-threonyl-[protein] + nicotinamide + H(+)

Direction not assertedBalance undeterminableRhea 72463

Page 558 of 629