Skip to content

Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

Atlas Graph Twin Access

Search the graph

Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

Atlas Graph Twin Access

Loading the page.

Catalyst

Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

The graph

Compounds
Outcomes
Proteins
Atlas
Interactions
Papers
Articles
Graph
Search

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases
Reactions
Reach

How it works

Mission
Method
Twin
How to read the evidence
Sources and licences

Build on it

Access
In your assistant
For agents
Query the graph
Bulk export

A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

13,651–13,700 of 31,435, by identifier

D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate
Left to rightBalancedRhea 13237
beta-L-fucose + ATP = beta-L-fucose 1-phosphate + ADP + H(+)
Direction not assertedBalancedRhea 13241
D-threo-isocitrate = glyoxylate + succinate
Direction not assertedBalancedRhea 13245
(R)-2-hydroxypropyl-coenzyme M + NAD(+) = 2-oxopropyl-coenzyme M + NADH + H(+)
Direction not assertedBalancedRhea 13249
1D-myo-inositol 1,3,4-trisphosphate + ATP = 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ADP + H(+)
ReversibleBalancedRhea 13253
1-amino-1-deoxy-scyllo-inositol 4-phosphate + L-arginine = 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate + L-ornithine
Direction not assertedBalancedRhea 13265
a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + H2O = an N-acylsphing-4-enine + D-glucose

Left to rightBalance undeterminableRhea 13269

an alpha-D-glucosyl-(1->6)-alpha-D-glucosyl-(1->6)-alpha-D-glucosyl-(1->3)-1-alkyl-2-acylglycerol + 3'-phosphoadenylyl sulfate = a 6-sulfo-alpha-D-glucosyl-(1->6)-alpha-D-glucosyl-(1->6)-alpha-D-glucosyl-(1->3)-1-alkyl-2-acylglycerol + adenosine 3',5'-bisphosphate + H(+)

Direction not assertedBalance undeterminableRhea 13273

[L-4-(L-arginin-2-N-yl)aspartate](n) + L-aspartate + ATP = [L-4-(L-arginin-2-N-yl)aspartate](n)-L-aspartate + ADP + phosphate + H(+)

Direction not assertedBalance undeterminableRhea 13277

(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA + NAD(+) = 2-methyl-3-oxobutanoyl-CoA + NADH + H(+)

Left to rightBalancedRhea 13281

L-cysteine + L-glutamate + ATP = gamma-L-glutamyl-L-cysteine + ADP + phosphate + H(+)

Left to rightBalancedRhea 13285

a di-trans,poly-cis-dolichyl phosphate + UDP-N-acetyl-alpha-D-glucosamine = an N-acetyl-alpha-D-glucosaminyl-diphospho-di-trans,poly-cis-dolichol + UMP

Left to rightBalance undeterminableRhea 13289

a sterol + a 1,2-diacyl-sn-glycerol = a sterol ester + a 1-acyl-sn-glycerol

Direction not assertedBalance undeterminableRhea 13301

(E)-sinapate + UDP-alpha-D-glucose = 1-O-(trans-sinapoyl)-beta-D-glucose + UDP

Direction not assertedBalancedRhea 13305

vanillin + NAD(+) + H2O = vanillate + NADH + 2 H(+)

Direction not assertedBalancedRhea 13309

sarcosine + O2 + H2O = formaldehyde + glycine + H2O2

Direction not assertedBalancedRhea 13313

(2R,3R)-tartrate + H(+) = (R)-glycerate + CO2

Direction not assertedBalancedRhea 13317

(R)-3,3-dimethylmalate + NAD(+) = 3-methyl-2-oxobutanoate + CO2 + NADH

Direction not assertedBalancedRhea 13321

UDP-N-acetyl-alpha-D-glucosamine + 2 NAD(+) + H2O = UDP-2-acetamido-2-deoxy-alpha-D-glucuronate + 2 NADH + 3 H(+)

Direction not assertedBalancedRhea 13325

a 3-oxosteroid + A = a 3-oxo-Delta(1)-steroid + AH2

Direction not assertedBalance undeterminableRhea 13329

beta-D-fructose 2,6-bisphosphate + H2O = beta-D-fructose 2-phosphate + phosphate

Direction not assertedBalancedRhea 13333

D-glucurono-6,2-lactone + H2O = D-glucuronate + H(+)

Direction not assertedBalancedRhea 13337

reduced [flavodoxin] + a menaquinone + 2 S-adenosyl-L-methionine = an 8-methylmenaquinone + oxidized [flavodoxin] + 5'-deoxyadenosine + L-methionine + S-adenosyl-L-homocysteine + 3 H(+)

Direction not assertedBalance undeterminableRhea 13341

L-cysteinyl-[protein] + (2E,6E)-farnesyl diphosphate = S-(2E,6E)-farnesyl-L-cysteinyl-[protein] + diphosphate

Direction not assertedBalance undeterminableRhea 13345

jasmonate + S-adenosyl-L-methionine = methyl (-)-jasmonate + S-adenosyl-L-homocysteine

Direction not assertedBalancedRhea 13349

4-O-[di(2R)-glycerylphospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n CDP-L-ribitol = 4-O-[(D-ribitylphospho)(n)-di{(2R)-glycerylphospho}]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n CMP + n H(+)

Direction not assertedBalance undeterminableRhea 13353

3-hydroxypropanoate + NAD(+) = 3-oxopropanoate + NADH + H(+)

Direction not assertedBalancedRhea 13357

sn-glycerol 3-phosphate + CTP + H(+) = CDP-glycerol + diphosphate

Direction not assertedBalancedRhea 13361

dimethylallyl diphosphate = isoprene + diphosphate

Direction not assertedBalancedRhea 13369

alpha-D-glucose 1-phosphate + ATP = alpha-D-glucose 1,6-bisphosphate + ADP + H(+)

Direction not assertedBalancedRhea 13377

an acyl-CoA + acetate = a carboxylate + acetyl-CoA

Direction not assertedBalance undeterminableRhea 13381

3-oxododecanoate + H(+) = 2-undecanone + CO2

Direction not assertedBalancedRhea 13385

glutaryl-CoA + oxidized [electron-transfer flavoprotein] + 2 H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein] + CO2

Direction not assertedBalance undeterminableRhea 13389

6-oxohexanoate + NADP(+) + H2O = hexanedioate + NADPH + 2 H(+)

Direction not assertedBalancedRhea 13397

(2E,6E)-farnesol = (2Z,6E)-farnesol

Direction not assertedBalancedRhea 13401

4-coumaroyl-CoA + agmatine = N-(4-guanidinobutyl)-4-hydroxycinnamamide + CoA + H(+)

Direction not assertedBalancedRhea 13405

7-aminomethyl-7-carbaguanine + 2 NADP(+) = 7-cyano-7-carbaguanine + 2 NADPH + 3 H(+)

Direction not assertedBalancedRhea 13409

thymidine + ADP = dTMP + AMP + H(+)

Direction not assertedBalancedRhea 13413

5,12-dihydroxanthommatin + NAD(+) = xanthommatin + NADH + H(+)

Direction not assertedBalancedRhea 13417

an N-acyl-D-mannosamine 6-phosphate + phosphoenolpyruvate + H2O = an N-acylneuraminate 9-phosphate + phosphate

Direction not assertedBalance undeterminableRhea 13421

a pyrimidine ribonucleoside 5'-phosphate + H2O = a pyrimidine nucleobase + D-ribose 5-phosphate

Direction not assertedBalance undeterminableRhea 13425

2-C-methyl-D-erythritol 4-phosphate + CTP + H(+) = 4-CDP-2-C-methyl-D-erythritol + diphosphate

Direction not assertedBalancedRhea 13429

2'-deoxycytidine + H2O + H(+) = 2'-deoxyuridine + NH4(+)

Left to rightBalancedRhea 13433

(E)-cinnamate + UDP-alpha-D-glucose = 1-O-(trans-cinnamoyl)-beta-D-glucose + UDP

Direction not assertedBalancedRhea 13437

L-cysteate + H2O = sulfite + pyruvate + NH4(+) + H(+)

Direction not assertedBalancedRhea 13441

(R)-pantetheine + H2O = cysteamine + (R)-pantothenate

Left to rightBalancedRhea 13445

2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + NADH + H(+)

Direction not assertedBalancedRhea 13449

quercetin + 3'-phosphoadenylyl sulfate = quercetin 3-sulfate + adenosine 3',5'-bisphosphate + H(+)

Direction not assertedBalancedRhea 13453

N(6)-[(R)-lipoyl]-L-lysyl-[protein] + 3-methyl-2-oxobutanoate + H(+) = N(6)-[(R)-S(8)-2-methylpropanoyldihydrolipoyl]-L-lysyl-[protein] + CO2

Left to rightBalance undeterminableRhea 13457

3,6,7,9-tetrahydroxy-3-methyl-2,3-dihydro-1H-naphtho[2,1-b]pyran-1-one + NADPH + O2 + H(+) = 2,3,4,7,9-pentahydroxy-6-methyl-1H-phenalen-1-one + NADP(+) + 2 H2O

Direction not assertedBalancedRhea 13461

Page 274 of 629