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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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AnatomyTissues, by what is expressed there
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MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Reactions
Reach

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

13,601–13,650 of 31,435, by identifier

vanillate + NADH + O2 + H(+) = 3,4-dihydroxybenzoate + formaldehyde + NAD(+) + H2O
Direction not assertedBalancedRhea 13021
3-methylbut-2-enoyl-CoA + N(6)-carboxybiotinyl-L-lysyl-[protein] = 3-methyl-(2E)-glutaconyl-CoA + N(6)-biotinyl-L-lysyl-[protein]
Direction not assertedBalance undeterminableRhea 13025
N-acetyl-D-glucosamine + O2 + H2O = N-acetyl-D-glucosaminate + H2O2 + H(+)
Direction not assertedBalancedRhea 13029
aldehydo-D-galactose 6-phosphate = keto-D-tagatose 6-phosphate
Direction not assertedBalancedRhea 13033
ATP + H2O + H(+) = ITP + NH4(+)
Direction not assertedBalancedRhea 13037
L-dopachrome = 5,6-dihydroxyindole-2-carboxylate
Direction not assertedBalancedRhea 13041
ent-kaur-16-ene + reduced [NADPH--hemoprotein reductase] + O2 = ent-kaur-16-en-19-ol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 13045

D-glucuronate = D-fructuronate

Direction not assertedBalancedRhea 13049

L-phenylalanine + pyruvate = 3-phenylpyruvate + L-alanine

Direction not assertedBalancedRhea 13053

an N-acylneuraminate 9-phosphate + H2O = an N-acylneuraminate + phosphate

Direction not assertedBalance undeterminableRhea 13057

S-sulfanylglutathione + O2 = glutathione S,S-dioxide + H(+)

Direction not assertedBalancedRhea 13061

ATP + H2O = ADP + phosphate + H(+)

Left to rightBalancedRhea 13065

ethanolamine + ATP = phosphoethanolamine + ADP + H(+)

Left to rightBalancedRhea 13069

guanosine 3'-diphosphate 5'-triphosphate + H2O = guanosine 3',5'-bis(diphosphate) + phosphate + H(+)

Direction not assertedBalancedRhea 13073

a D-hexose + an acyl phosphate = a D-hexose phosphate + a carboxylate + H(+)

Direction not assertedBalance undeterminableRhea 13077

biotin amide + H2O = biotin + NH4(+)

Left to rightBalancedRhea 13081

(S)-2,3,4,5-tetrahydrodipicolinate + acetyl-CoA + H2O = L-2-acetamido-6-oxoheptanedioate + CoA

Direction not assertedBalancedRhea 13085

6 Fe(III)-[cytochrome c] + NH4(+) + 2 H2O = 6 Fe(II)-[cytochrome c] + nitrite + 8 H(+)

Direction not assertedBalance undeterminableRhea 13089

an N-acylsphing-4-enine + UDP-alpha-D-galactose = a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + UDP + H(+)

Left to rightBalance undeterminableRhea 13093

a (3R)-hydroxyacyl-[ACP] = a (2E)-enoyl-[ACP] + H2O

Left to rightBalance undeterminableRhea 13097

4-imidazolone-5-propanoate = trans-urocanate + H2O

Direction not assertedBalancedRhea 13101

glycerol 2-phosphate + H2O = glycerol + phosphate

Left to rightBalancedRhea 13105

2-acetamidofluorene + NAD(+) + H2O = N-hydroxy-2-acetamidofluorene + NADH + H(+)

Direction not assertedBalancedRhea 13109

2-acetamidofluorene + NADP(+) + H2O = N-hydroxy-2-acetamidofluorene + NADPH + H(+)

Direction not assertedBalancedRhea 13113

pyrazole + O-acetyl-L-serine = 3-(pyrazol-1-yl)-L-alanine + acetate + H(+)

Direction not assertedBalancedRhea 13117

shikimate + ATP = 3-phosphoshikimate + ADP + H(+)

Direction not assertedBalancedRhea 13121

glutathione disulfide + CoA = CoA-glutathione + glutathione

Direction not assertedBalancedRhea 13125

cis-4-coumarate + UDP-alpha-D-glucose = 4'-O-beta-D-glucosyl-cis-4-coumarate + UDP + H(+)

Direction not assertedBalancedRhea 13129

a di-trans,poly-cis-dolichol + CTP = a di-trans,poly-cis-dolichyl phosphate + CDP + H(+)

Left to rightBalance undeterminableRhea 13133

cycloartenol + S-adenosyl-L-methionine = cyclolaudenol + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 13137

2-methylpropanoyl-CoA = butanoyl-CoA

Direction not assertedBalancedRhea 13141

4-O-beta-D-mannopyranosyl-N-acetyl-D-glucosamine + phosphate = alpha-D-mannose 1-phosphate + N-acetyl-D-glucosamine

Direction not assertedBalancedRhea 13145

A + NADPH + H(+) = AH2 + NADP(+)

Direction not assertedBalancedRhea 13149

(R)-glycerate + CO2 + NAD(+) = 2-hydroxy-3-oxosuccinate + NADH + 2 H(+)

Direction not assertedBalancedRhea 13153

(R)-glycerate + CO2 + NADP(+) = 2-hydroxy-3-oxosuccinate + NADPH + 2 H(+)

Direction not assertedBalancedRhea 13157

L-threonine + NAD(+) = (2S)-2-amino-3-oxobutanoate + NADH + H(+)

Direction not assertedBalancedRhea 13161

maleate = fumarate

Direction not assertedBalancedRhea 13169

phosphite + NAD(+) + H2O = phosphate + NADH + 3 H(+)

Direction not assertedBalancedRhea 13173

6-phospho-5-dehydro-2-deoxy-D-gluconate = 3-oxopropanoate + dihydroxyacetone phosphate

Direction not assertedBalancedRhea 13177

nitrate(out) + ATP + H2O = nitrate(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 13181

4 porphobilinogen + H2O = hydroxymethylbilane + 4 NH4(+)

Left to rightBalancedRhea 13185

a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + 2 H2O = 3-beta-D-galactosyl-sn-glycerol + 2 a fatty acid + 2 H(+)

Left to rightBalance undeterminableRhea 13189

5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + H(+) = 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

Direction not assertedBalancedRhea 13193

sulfite + UDP-alpha-D-glucose + H(+) = UDP-alpha-D-6-sulfoquinovose + H2O

Direction not assertedBalancedRhea 13197

L-arginine + glycine = guanidinoacetate + L-ornithine

Left to rightBalancedRhea 13201

a monosaccharide 1-phosphate + UTP + H(+) = a UDP-monosaccharide + diphosphate

Direction not assertedBalance undeterminableRhea 13205

succinate semialdehyde + NADP(+) + H2O = succinate + NADPH + 2 H(+)

Direction not assertedBalancedRhea 13213

succinate semialdehyde + NAD(+) + H2O = succinate + NADH + 2 H(+)

Left to rightBalancedRhea 13217

(R)-mevalonate + NAD(+) = (R)-mevaldate + NADH + H(+)

Direction not assertedBalancedRhea 13221

guanosine + phosphate = alpha-D-ribose 1-phosphate + guanine

Left to rightBalancedRhea 13233

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