Proteins/UNIPROT:Q6ZN44

UNC5A

ProteinUNIPROT:Q6ZN44

Receptor for netrin required for axon guidance. Functions in the netrin signaling pathway and promotes neurite outgrowth in response to NTN1. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand..

Function from UniProtKB (Q6ZN44), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

51 statements

51 statements · 3 reference databases · Subject: UNC5A · Sources: Hetionet, Reactome, WikiPathways

Order

ABCA2 covaries with UNC5AProteinHetionet hetionet:covaries:20-90249Inferred only
UNC5A covaries with ADAMTS10ProteinHetionet hetionet:covaries:81794-90249Inferred only
UNC5A covaries with ATP13A1ProteinHetionet hetionet:covaries:57130-90249Inferred only
UNC5A covaries with CAND2ProteinHetionet hetionet:covaries:23066-90249Inferred only
CLEC2L covaries with UNC5AProteinHetionet hetionet:covaries:154790-90249Inferred only
CLIP2 covaries with UNC5AProteinHetionet hetionet:covaries:7461-90249Inferred only
UNC5A covaries with CLSTN2ProteinHetionet hetionet:covaries:64084-90249Inferred only
UNC5A covaries with COMPProteinHetionet hetionet:covaries:1311-90249Inferred only
UNC5A covaries with CUEDC2ProteinHetionet hetionet:covaries:79004-90249Inferred only
UNC5A covaries with DDX39AProteinHetionet hetionet:covaries:10212-90249Inferred only
UNC5A covaries with DHX30ProteinHetionet hetionet:covaries:22907-90249Inferred only
UNC5A covaries with EPB41L1ProteinHetionet hetionet:covaries:2036-90249Inferred only

Show the remaining 39

UNC5A covaries with EVA1CProteinHetionet hetionet:covaries:59271-90249Inferred only
UNC5A covaries with FAM168AProteinHetionet hetionet:covaries:23201-90249Inferred only
UNC5A covaries with FEM1BProteinHetionet hetionet:covaries:10116-90249Inferred only
FGFR4 covaries with UNC5AProteinHetionet hetionet:covaries:2264-90249Inferred only
UNC5A covaries with GPR62ProteinHetionet hetionet:covaries:118442-90249Inferred only
GRK6 covaries with UNC5AProteinHetionet hetionet:covaries:2870-90249Inferred only
H2BC4; H2BC6; H2BC7; H2BC8; H2BC10 covaries with UNC5AProteinHetionet hetionet:covaries:8347-90249Inferred only
UNC5A covaries with HAPSTR1ProteinHetionet hetionet:covaries:29035-90249Inferred only
HOXA1 covaries with UNC5AProteinHetionet hetionet:covaries:3198-90249Inferred only
HYAL3 covaries with UNC5AProteinHetionet hetionet:covaries:8372-90249Inferred only
UNC5A covaries with IGLON5ProteinHetionet hetionet:covaries:402665-90249Inferred only
UNC5A covaries with KANSL1ProteinHetionet hetionet:covaries:284058-90249Inferred only
UNC5A covaries with LARP6ProteinHetionet hetionet:covaries:55323-90249Inferred only
MYC covaries with UNC5AProteinHetionet hetionet:covaries:4609-90249Inferred only
UNC5A covaries with NCSTNProteinHetionet hetionet:covaries:23385-90249Inferred only
UNC5A covaries with PAN2ProteinHetionet hetionet:covaries:90249-9924Inferred only
UNC5A covaries with PARP16ProteinHetionet hetionet:covaries:54956-90249Inferred only
UNC5A covaries with PRKRAProteinHetionet hetionet:covaries:8575-90249Inferred only
UNC5A covaries with RNF44ProteinHetionet hetionet:covaries:22838-90249Inferred only
UNC5A covaries with SBK1ProteinHetionet hetionet:covaries:388228-90249Inferred only
UNC5A covaries with SNORCProteinHetionet hetionet:covaries:389084-90249Inferred only
UNC5A covaries with SP7ProteinHetionet hetionet:covaries:121340-90249Inferred only
UNC5A covaries with TBX5ProteinHetionet hetionet:covaries:6910-90249Inferred only
UNC5A covaries with THADAProteinHetionet hetionet:covaries:63892-90249Inferred only
TNMD covaries with UNC5AProteinHetionet hetionet:covaries:64102-90249Inferred only
UNC5A covaries with WNT9AProteinHetionet hetionet:covaries:7483-90249Inferred only
UNC5A covaries with WSCD2ProteinHetionet hetionet:covaries:90249-9671Inferred only
MAGED1 interacts with UNC5AProteinHetionet hetionet:interacts:90249-9500Inferred only
NTN1 interacts with UNC5AProteinHetionet hetionet:interacts:90249-9423Inferred only
UNC5A participates in 5q35 copy number variationPathwayWikiPathways WP5380Inferred only
UNC5A participates in ApoptosisPathwayReactome R-HSA-109581Inferred only
UNC5A participates in Axon guidancePathwayReactome R-HSA-422475Inferred only
UNC5A participates in Caspase activation via Dependence Receptors in the absence of ligandPathwayReactome R-HSA-418889Inferred only
UNC5A participates in Caspase activation via extrinsic apoptotic signalling pathwayPathwayReactome R-HSA-5357769Inferred only
UNC5A participates in Developmental BiologyPathwayReactome R-HSA-1266738Inferred only
UNC5A participates in Nervous system developmentPathwayReactome R-HSA-9675108Inferred only
UNC5A participates in Netrin mediated repulsion signalsPathwayReactome R-HSA-418886Inferred only
UNC5A participates in Netrin-1 signalingPathwayReactome R-HSA-373752Inferred only
UNC5A participates in Programmed Cell DeathPathwayReactome R-HSA-5357801Inferred only

Other names

6 names

Resolves to: UNC5A

Also called: KIAA1976Protein unc-5 homolog 1Protein unc-5 homolog Aunc-5 homolog 1unc-5 homolog AUNC5H1

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