Proteins/UNIPROT:P45378

TNNT3

ProteinUNIPROT:P45378

Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

Function from UniProtKB (P45378), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

6 rows

arthrogryposis, distal, type 2B2 has a germline basis in TNNT3DiseaseGenCC HGNC:11950|MONDO:0032750Inferred only
congenital myopathy has a germline basis in TNNT3DiseaseGenCC HGNC:11950|MONDO:0019952Inferred only
digitotalar dysmorphism has a germline basis in TNNT3DiseaseGenCC HGNC:11950|MONDO:0015240Inferred only
distal arthrogryposis type 2B1 has a germline basis in TNNT3DiseaseGenCC HGNC:11950|MONDO:0020820Inferred only
nemaline myopathy has a germline basis in TNNT3DiseaseGenCC HGNC:11950|MONDO:0018958Inferred only
Sheldon-hall syndrome has a germline basis in TNNT3DiseaseGenCC HGNC:11950|MONDO:0011128Inferred only

Statements

34 statements

34 statements · 4 reference databases · Subject: TNNT3 · Sources: gene ontology, Hetionet, Reactome, WikiPathways

Order

ARFRP1 covaries with TNNT3ProteinHetionet hetionet:covaries:10139-7140Inferred only
ATP2A1 covaries with TNNT3ProteinHetionet hetionet:covaries:487-7140Inferred only
BUD31 covaries with TNNT3ProteinHetionet hetionet:covaries:7140-8896Inferred only
CHST10 covaries with TNNT3ProteinHetionet hetionet:covaries:7140-9486Inferred only
CNFN covaries with TNNT3ProteinHetionet hetionet:covaries:7140-84518Inferred only
CYFIP1 covaries with TNNT3ProteinHetionet hetionet:covaries:23191-7140Inferred only
EIF3D covaries with TNNT3ProteinHetionet hetionet:covaries:7140-8664Inferred only
KRT17 covaries with TNNT3ProteinHetionet hetionet:covaries:3872-7140Inferred only
KRT80 covaries with TNNT3ProteinHetionet hetionet:covaries:144501-7140Inferred only
LANCL2 covaries with TNNT3ProteinHetionet hetionet:covaries:55915-7140Inferred only
NR2C2 covaries with TNNT3ProteinHetionet hetionet:covaries:7140-7182Inferred only
TNNT3 covaries with PAQR7ProteinHetionet hetionet:covaries:164091-7140Inferred only

Show the remaining 22

PPP6C covaries with TNNT3ProteinHetionet hetionet:covaries:5537-7140Inferred only
PRPH covaries with TNNT3ProteinHetionet hetionet:covaries:5630-7140Inferred only
SLC16A3 covaries with TNNT3ProteinHetionet hetionet:covaries:7140-9123Inferred only
TNNT3 covaries with TIMM17AProteinHetionet hetionet:covaries:10440-7140Inferred only
TNNT3 covaries with TNNT2ProteinHetionet hetionet:covaries:7139-7140Inferred only
TPST1 covaries with TNNT3ProteinHetionet hetionet:covaries:7140-8460Inferred only
TRPV6 covaries with TNNT3ProteinHetionet hetionet:covaries:55503-7140Inferred only
UBXN6 covaries with TNNT3ProteinHetionet hetionet:covaries:7140-80700Inferred only
YPEL4 covaries with TNNT3ProteinHetionet hetionet:covaries:219539-7140Inferred only
TNNT3 interacts with HAP1ProteinHetionet hetionet:interacts:7140-9001Inferred only
TNNT3 interacts with NUDT3ProteinHetionet hetionet:interacts:11165-7140Inferred only
TNNT3 interacts with SNUPNProteinHetionet hetionet:interacts:10073-7140Inferred only
TNNI2 interacts with TNNT3ProteinHetionet hetionet:interacts:7136-7140Inferred only
TNNT3 interacts with TRIM63ProteinHetionet hetionet:interacts:7140-84676Inferred only
TNNT3 interacts with TSG101ProteinHetionet hetionet:interacts:7140-7251Inferred only
TNNT3 participates in Caffeine in myocytesPathwayWikiPathways WP5603Inferred only
TNNT3 participates in Muscle contractionPathwayReactome R-HSA-397014Inferred only
TNNT3 participates in Striated Muscle ContractionPathwayReactome R-HSA-390522Inferred only
TNNT3 participates in Striated muscle contraction pathwayPathwayWikiPathways WP383Inferred only
TNNT3 regulates positive regulation of calcium-dependent ATPase activityBiological processgene ontology P45378|GO:1903612Inferred only
TNNT3 regulates regulation of ATP-dependent activityBiological processgene ontology P45378|GO:0043462Inferred only
TNNT3 regulates regulation of striated muscle contractionBiological processgene ontology P45378|GO:0006942Inferred only

Other names

4 names

Resolves to: TNNT3

Also called: Beta-TnTFFast skeletal muscle troponin TfTnTTnTf

← Every protein Find it in the graph →