Proteins/UNIPROT:O95407

TNFRSF6B

ProteinUNIPROT:O95407

Soluble decoy receptor that binds and neutralizes the TNF-family ligands TNFSF14/LIGHT, TNFSF15, and FASLG, preventing them from interacting with their cognate receptors and thereby blocking apoptosis and other immune-signaling pathway..

Function from UniProtKB (O95407), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

36 statements

36 statements · 4 reference databases · Subject: TNFRSF6B · Sources: gene ontology, Hetionet, Reactome, WikiPathways

Order

TNFRSF6B covaries with CALM1ProteinHetionet hetionet:covaries:801-8771Inferred only
DBN1 covaries with TNFRSF6BProteinHetionet hetionet:covaries:1627-8771Inferred only
KDELR3 covaries with TNFRSF6BProteinHetionet hetionet:covaries:11015-8771Inferred only
TNFRSF6B covaries with LENEPProteinHetionet hetionet:covaries:55891-8771Inferred only
PACSIN1 covaries with TNFRSF6BProteinHetionet hetionet:covaries:29993-8771Inferred only
RDH10 covaries with TNFRSF6BProteinHetionet hetionet:covaries:157506-8771Inferred only
TNFRSF6B covaries with SF3B4ProteinHetionet hetionet:covaries:10262-8771Inferred only
TNFRSF6B covaries with SRP54ProteinHetionet hetionet:covaries:6729-8771Inferred only
TCEA2 covaries with TNFRSF6BProteinHetionet hetionet:covaries:6919-8771Inferred only
TNFRSF6B covaries with TMED2ProteinHetionet hetionet:covaries:10959-8771Inferred only
TNFRSF6B covaries with TRAF7ProteinHetionet hetionet:covaries:84231-8771Inferred only
TNFRSF6B covaries with UBE2MProteinHetionet hetionet:covaries:8771-9040Inferred only

Show the remaining 24

FASLG interacts with TNFRSF6BProteinHetionet hetionet:interacts:356-8771Inferred only
PPP1R7 interacts with TNFRSF6BProteinHetionet hetionet:interacts:5510-8771Inferred only
TNFSF14 interacts with TNFRSF6BProteinHetionet hetionet:interacts:8740-8771Inferred only
TNFRSF6B interacts with TNFSF15ProteinHetionet hetionet:interacts:8771-9966Inferred only
TNFRSF6B participates in Apoptosis modulation and signalingPathwayWikiPathways WP1772Inferred only
TNFRSF6B participates in Cytokine Signaling in Immune systemPathwayReactome R-HSA-1280215Inferred only
TNFRSF6B participates in Immune SystemPathwayReactome R-HSA-168256Inferred only
TNFRSF6B participates in TNFR2 non-canonical NF-kB pathwayPathwayReactome R-HSA-5668541Inferred only
TNFRSF6B participates in TNFs bind their physiological receptorsPathwayReactome R-HSA-5669034Inferred only
TNFRSF6B regulates negative regulation of apoptotic processBiological processgene ontology O95407|GO:0043066Inferred only
TNFRSF6B regulates negative regulation of inflammatory responseBiological processgene ontology O95407|GO:0050728Inferred only
TNFRSF6B increases the expression of C2CD2ProteinHetionet hetionet:regulates:8771-25966Inferred only
TNFRSF6B decreases the expression of CHMP4AProteinHetionet hetionet:regulates:8771-29082Inferred only
TNFRSF6B increases the expression of HERPUD1ProteinHetionet hetionet:regulates:8771-9709Inferred only
TNFRSF6B increases the expression of HOOK2ProteinHetionet hetionet:regulates:8771-29911Inferred only
TNFRSF6B increases the expression of MALProteinHetionet hetionet:regulates:8771-4118Inferred only
TNFRSF6B increases the expression of MCOLN1ProteinHetionet hetionet:regulates:8771-57192Inferred only
TNFRSF6B increases the expression of ME2ProteinHetionet hetionet:regulates:8771-4200Inferred only
TNFRSF6B decreases the expression of RPA1ProteinHetionet hetionet:regulates:8771-6117Inferred only
TNFRSF6B decreases the expression of RPIAProteinHetionet hetionet:regulates:8771-22934Inferred only
TNFRSF6B increases the expression of SERPINA3ProteinHetionet hetionet:regulates:8771-12Inferred only
TNFRSF6B increases the expression of SNX11ProteinHetionet hetionet:regulates:8771-29916Inferred only
TNFRSF6B decreases the expression of SPAG7ProteinHetionet hetionet:regulates:8771-9552Inferred only
TNFRSF6B decreases the expression of STUB1ProteinHetionet hetionet:regulates:8771-10273Inferred only

Other names

5 names

Resolves to: TNFRSF6B

Also called: DCR3Decoy receptor 3Decoy receptor for Fas ligandM68TR6

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