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Proteins/UNIPROT:Q9NX78
O-mannosyl-transferase that transfers mannosyl residues to the hydroxyl group of serine or threonine residues of proteins. Specifically glycosylates the IPT/TIG domain of target proteins, such as MET and MST1R/RON. TMEM260-mediated O-mannosylated residues are composed of single mannose glycans that are not elongated or modified..
Function from UniProtKB (Q9NX78), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
6 statements
6 statements · 1 reference database · Subject: TMEM260 · Sources: Hetionet
2 reactions
a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate+L-seryl-[protein]3-O-(alpha-D-mannosyl)-L-seryl-[protein]+a di-trans,poly-cis-dolichyl phosphate+hydron
Catalysed by TMTC3 or TMTC1 or TMTC2 or TMEM260 or POMT2 or POMT1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:17377CC BY 4.0Reference data
a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate+L-threonyl-[protein]3-O-(alpha-D-mannosyl)-L-threonyl-[protein]
2 names
Resolves to: TMEM260
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:53396CC BY 4.0Reference data