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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Proteins/UNIPROT:O95932

TGM6

Protein·UNIPROT:O95932

Open in the graph

Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins..

Function from UniProtKB (O95932), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

GenCC submitters' classifications

1 row

spinocerebellar ataxia type 35 has a germline basis in TGM6DiseaseGenCC HGNC:16255|MONDO:0013485Inferred only

Statements

2 statements

2 statements · 2 reference databases · Subject: TGM6 · Sources: Hetionet, UniProt

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PRPS1L1 covaries with TGM6ProteinHetionet hetionet:covaries:221823-343641Inferred only
TGM6 requires the cofactor Ca(2+)CompoundUniProt O95932Inferred only

Reactions

2 reactions

MAM00201c+MAM01310cMAM00207c+ammonium
Catalysed by TGM1 or TGM5 or F13A1 or TGM3 or F13B or TGM7 or TGM6 or TGM2
Reaction pageLeft to rightBalance undeterminableEC 2.3.2.13cytosol
Human-GEM MAR09496CC BY 4.0Reference data
L-glutaminyl-[protein]+L-lysyl-[protein][protein]-L-lysyl-N(6)-5-L-glutamyl-[protein]

Other names

9 names

Resolves to: TGM6

Also called: TG6TGase YTGase-3-likeTGase-6TGM3LTGYTransglutaminase YTransglutaminase-3-likeTransglutaminase-6

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Catalysed by TGM5 or TGM6 or F13A1 or TGM2 or TGM1 or TGM3 or TGM7

Reaction pageLeft to rightBalance undeterminable

Rhea RHEA:54816CC BY 4.0Reference data