Proteins/UNIPROT:P0C1Z6

TFPT

ProteinUNIPROT:P0C1Z6

Appears to promote apoptosis in a p53/TP53-independent manner.

Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.

Function from UniProtKB (P0C1Z6), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

33 statements

33 statements · 3 reference databases · Subject: TFPT · Sources: gene ontology, Hetionet, Reactome

Order

APP interacts with TFPTProteinHetionet hetionet:interacts:29844-351Inferred only
TFPT interacts with EAF1ProteinHetionet hetionet:interacts:29844-85403Inferred only
TFPT interacts with EAF2ProteinHetionet hetionet:interacts:29844-55840Inferred only
ELL interacts with TFPTProteinHetionet hetionet:interacts:29844-8178Inferred only
NOL3 interacts with TFPTProteinHetionet hetionet:interacts:29844-8996Inferred only
PAWR interacts with TFPTProteinHetionet hetionet:interacts:29844-5074Inferred only
RUNDC3A interacts with TFPTProteinHetionet hetionet:interacts:10900-29844Inferred only
SUMO2 interacts with TFPTProteinHetionet hetionet:interacts:29844-6613Inferred only
TCF3 interacts with TFPTProteinHetionet hetionet:interacts:29844-6929Inferred only
TPM3 interacts with TFPTProteinHetionet hetionet:interacts:29844-7170Inferred only
TFPT interacts with UCHL5ProteinHetionet hetionet:interacts:29844-51377Inferred only
TFPT participates in DeubiquitinationPathwayReactome R-HSA-5688426Inferred only

Show the remaining 21

TFPT participates in DNA Damage Recognition in GG-NERPathwayReactome R-HSA-5696394Inferred only
TFPT participates in DNA RepairPathwayReactome R-HSA-73894Inferred only
TFPT participates in Global Genome Nucleotide Excision Repair (GG-NER)PathwayReactome R-HSA-5696399Inferred only
TFPT participates in Metabolism of proteinsPathwayReactome R-HSA-392499Inferred only
TFPT participates in Nucleotide Excision RepairPathwayReactome R-HSA-5696398Inferred only
TFPT participates in Post-translational protein modificationPathwayReactome R-HSA-597592Inferred only
TFPT participates in UCH proteinasesPathwayReactome R-HSA-5689603Inferred only
TFPT regulates positive regulation of apoptotic processBiological processgene ontology P0C1Z6|GO:0043065Inferred only
TFPT regulates positive regulation of DNA repairBiological processgene ontology P0C1Z6|GO:0045739Inferred only
TFPT regulates positive regulation of DNA-templated transcriptionBiological processgene ontology P0C1Z6|GO:0045893Inferred only
TFPT regulates positive regulation of telomere maintenance in response to DNA damageBiological processgene ontology P0C1Z6|GO:1904507Inferred only
TFPT regulates regulation of cell cycleBiological processgene ontology P0C1Z6|GO:0051726Inferred only
TFPT regulates regulation of chromosome organizationBiological processgene ontology P0C1Z6|GO:0033044Inferred only
TFPT regulates regulation of DNA replicationBiological processgene ontology P0C1Z6|GO:0006275Inferred only
TFPT regulates regulation of DNA strand elongationBiological processgene ontology P0C1Z6|GO:0060382Inferred only
TFPT regulates regulation of embryonic developmentBiological processgene ontology P0C1Z6|GO:0045995Inferred only
ACBD3 decreases the expression of TFPTProteinHetionet hetionet:regulates:64746-29844Inferred only
FOXA2 decreases the expression of TFPTProteinHetionet hetionet:regulates:3170-29844Inferred only
GSTZ1 increases the expression of TFPTProteinHetionet hetionet:regulates:2954-29844Inferred only
HERPUD1 increases the expression of TFPTProteinHetionet hetionet:regulates:9709-29844Inferred only
METTL1 decreases the expression of TFPTProteinHetionet hetionet:regulates:4234-29844Inferred only

Other names

4 names

Resolves to: TFPT

Also called: FB1INO80 complex subunit FINO80FProtein FB1

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