Proteins/UNIPROT:P57105

SYNJ2BP

ProteinUNIPROT:P57105

Regulates endocytosis of activin type 2 receptor kinases through the Ral/RALBP1-dependent pathway and may be involved in suppression of activin-induced signal transduction..

Function from UniProtKB (P57105), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

18 statements

18 statements · 2 reference databases · Subject: SYNJ2BP · Sources: gene ontology, Hetionet

Order

ACTB interacts with SYNJ2BPProteinHetionet hetionet:interacts:55333-60Inferred only
ACVR2A interacts with SYNJ2BPProteinHetionet hetionet:interacts:55333-92Inferred only
ACVR2B interacts with SYNJ2BPProteinHetionet hetionet:interacts:55333-93Inferred only
APP interacts with SYNJ2BPProteinHetionet hetionet:interacts:351-55333Inferred only
LRP1 interacts with SYNJ2BPProteinHetionet hetionet:interacts:4035-55333Inferred only
LRP2 interacts with SYNJ2BPProteinHetionet hetionet:interacts:4036-55333Inferred only
LRP8 interacts with SYNJ2BPProteinHetionet hetionet:interacts:55333-7804Inferred only
RALBP1 interacts with SYNJ2BPProteinHetionet hetionet:interacts:10928-55333Inferred only
SYNJ2 interacts with SYNJ2BPProteinHetionet hetionet:interacts:55333-8871Inferred only
UBC interacts with SYNJ2BPProteinHetionet hetionet:interacts:55333-7316Inferred only
SYNJ2BP regulates negative regulation of angiogenesisBiological processgene ontology P57105|GO:0016525Inferred only
SYNJ2BP regulates negative regulation of endothelial cell migrationBiological processgene ontology P57105|GO:0010596Inferred only

Show the remaining 6

SYNJ2BP regulates negative regulation of endothelial cell proliferationBiological processgene ontology P57105|GO:0001937Inferred only
SYNJ2BP regulates negative regulation of ERK1 and ERK2 cascadeBiological processgene ontology P57105|GO:0070373Inferred only
SYNJ2BP regulates negative regulation of sprouting angiogenesisBiological processgene ontology P57105|GO:1903671Inferred only
SYNJ2BP regulates regulation of Notch signaling pathwayBiological processgene ontology P57105|GO:0008593Inferred only
NRP1 decreases the expression of SYNJ2BPProteinHetionet hetionet:regulates:8829-55333Inferred only
PHF1 increases the expression of SYNJ2BPProteinHetionet hetionet:regulates:5252-55333Inferred only

Other names

3 names

Resolves to: SYNJ2BP

Also called: Mitochondrial outer membrane protein 25OMP25Synaptojanin-2-binding protein

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