Loading the page.
Proteins/UNIPROT:Q16143
Non-amyloid component of senile plaques found in Alzheimer disease. Could act as a regulator of SNCA aggregation process. Protects neurons from staurosporine and 6-hydroxy dopamine (6OHDA)-stimulated caspase activation in a p53/TP53-dependent manner. Contributes to restore the SNCA anti-apoptotic function abolished by 6OHDA. Not found in the Lewy bodies associated with Parkinson disease.
Function from UniProtKB (Q16143), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
29 statements
29 statements · 3 reference databases · Subject: SNCB · Sources: Hetionet, Reactome, WikiPathways
1 name
Resolves to: SNCB