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A reference for what the literature reports. Not medical advice.

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Proteins/UNIPROT:Q8IZ73

RPUSD2

Protein·UNIPROT:Q8IZ73

Open in the graph

Pseudouridine synthase that catalyzes pseudouridylation of mRNAs. In addition, it catalyzes the formation of pseudouridine mainly at positions 31 and 32 in the anticodon loop of cytosolic and mitochondrial tRNAs, and at position 34 of certain cytosolic tRNAs such as tRNA(Ile)..

Function from UniProtKB (Q8IZ73), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

4 statements

4 statements · 1 reference database · Subject: RPUSD2 · Sources: Hetionet

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OR13C2 covaries with RPUSD2ProteinHetionet hetionet:covaries:27079-392376Inferred only
ZFYVE19 covaries with RPUSD2ProteinHetionet hetionet:covaries:27079-84936Inferred only
APP interacts with RPUSD2ProteinHetionet hetionet:interacts:27079-351Inferred only
GRB2 interacts with RPUSD2ProteinHetionet hetionet:interacts:27079-2885Inferred only

Reactions

4 reactions

CHEBI:65315CHEBI:65314
Catalysed by RPUSD2
Reaction pageDirection not assertedBalanced
Rhea RHEA:42544CC BY 4.0Reference data
CHEBI:65315CHEBI:65314
Catalysed by RPUSD2
Reaction pageDirection not assertedBalanced
Rhea RHEA:42552CC BY 4.0Reference data
a uridine in tRNAa pseudouridine in tRNA
Catalysed by RPUSD2 or TRUB1 or RPUSD4 or

Other names

2 names

Resolves to: RPUSD2

Also called: C15orf19RNA pseudouridylate synthase domain-containing protein 2

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or PUS1

Reaction pageLeft to rightBalance undeterminable

Rhea RHEA:54572CC BY 4.0Reference data

a uridine in mRNAa pseudouridine in mRNA

Catalysed by TRUB2 or RPUSD3 or RPUSD2 or TRUB1 or RPUSD4 or PUS7 or PUS7L or PUS1

Reaction pageLeft to rightBalance undeterminable

Rhea RHEA:56644CC BY 4.0Reference data