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Proteins/UNIPROT:Q02833
Negatively regulates stress-induced JNK activation and apoptosis by promoting MAP2K7 phosphorylation and inhibiting its ability to activate JNK. Following prolonged stress, anti-apoptotic effect stops because of degradation of RASSF7 protein via the ubiquitin-proteasome pathway. Required for the activation of AURKB and chromosomal congression during mitosis where it stimulates microtubule polymerization..
Function from UniProtKB (Q02833), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
75 statements
75 statements · 2 reference databases · Subject: RASSF7 · Sources: Hetionet, WikiPathways
4 names
Resolves to: RASSF7