Proteins/UNIPROT:Q86VX9

MON1A

ProteinUNIPROT:Q86VX9

Plays an important role in membrane trafficking through the secretory apparatus. Not involved in endocytic trafficking to lysosomes (By similarity). Acts in concert with CCZ1, as a guanine exchange factor (GEF) for RAB7, promotes the exchange of GDP to GTP, converting it from an inactive GDP-bound form into an active GTP-bound form..

Function from UniProtKB (Q86VX9), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

13 statements

13 statements · 2 reference databases · Subject: MON1A · Sources: Hetionet, Reactome

Order

KCNIP4 covaries with MON1AProteinHetionet hetionet:covaries:80333-84315Inferred only
MON1A covaries with MYOD1ProteinHetionet hetionet:covaries:4654-84315Inferred only
GFI1B interacts with MON1AProteinHetionet hetionet:interacts:8328-84315Inferred only
MAPK6 interacts with MON1AProteinHetionet hetionet:interacts:5597-84315Inferred only
RABGEF1 interacts with MON1AProteinHetionet hetionet:interacts:27342-84315Inferred only
RGS2 interacts with MON1AProteinHetionet hetionet:interacts:5997-84315Inferred only
TAB1 interacts with MON1AProteinHetionet hetionet:interacts:10454-84315Inferred only
UBC interacts with MON1AProteinHetionet hetionet:interacts:7316-84315Inferred only
VPS33A interacts with MON1AProteinHetionet hetionet:interacts:65082-84315Inferred only
MON1A participates in Membrane TraffickingPathwayReactome R-HSA-199991Inferred only
MON1A participates in RAB GEFs exchange GTP for GDP on RABsPathwayReactome R-HSA-8876198Inferred only
MON1A participates in Rab regulation of traffickingPathwayReactome R-HSA-9007101Inferred only

Show the remaining 1

MON1A participates in Vesicle-mediated transportPathwayReactome R-HSA-5653656Inferred only

Other names

2 names

Resolves to: MON1A

Also called: SAND1Vacuolar fusion protein MON1 homolog A

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