Skip to content

Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

Atlas Graph Twin Access

Search the graph

Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

Atlas Graph Twin Access

Loading the page.

Catalyst

Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

The graph

Compounds
Outcomes
Proteins
Atlas
Interactions
Papers
Articles
Graph
Search

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases
Reactions
Reach

How it works

Mission
Method
Twin
How to read the evidence
Sources and licences

Build on it

Access
In your assistant
For agents
Query the graph
Bulk export

A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Proteins/UNIPROT:Q86X67

NUDT13

Protein·UNIPROT:Q86X67NAD(P)H pyrophosphatase NUDT13, mitochondrial

Open in the graph

NAD(P)H pyrophosphatase that hydrolyzes NADH into NMNH and AMP, and NADPH into NMNH and 2',5'-ADP. Has a marked preference for the reduced pyridine nucleotides. Does not show activity toward NAD-capped RNAs; the NAD-cap is an atypical cap present at the 5'-end of some RNAs..

Function from UniProtKB (Q86X67), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

7 statements

7 statements · 3 reference databases · Subject: NUDT13 · Sources: Hetionet, Reactome, UniProt

Search this listOrder

NUDT13 covaries with CD1BProteinHetionet hetionet:covaries:25961-910Inferred only
UBD interacts with NUDT13ProteinHetionet hetionet:interacts:10537-25961Inferred only
NUDT13 participates in Interconversion of nucleotide di- and triphosphatesPathwayReactome R-HSA-499943Inferred only
NUDT13 participates in MetabolismPathwayReactome R-HSA-1430728Inferred only
NUDT13 participates in Metabolism of nucleotidesPathwayReactome R-HSA-15869Inferred only
NUDT13 requires the cofactor magnesium(2+)CompoundUniProt Q86X67Inferred only
NUDT13 requires the cofactor Mn(2+)CompoundUniProt Q86X67Inferred only

Reactions

3 reactions

NAD(1-)+waterNMN zwitterion+AMP+2hydron
Catalysed by NUDT13 or NUDT12 or ENPP5
Reaction pageLeft to rightBalanced
Rhea RHEA:11800CC BY 4.0Reference data
NADH(2-)+waterreduced beta-nicotinamide D-ribonucleotide+AMP+2hydron

Other names

5 names

Resolves to: NUDT13

Also called: KiSS-16Nucleoside diphosphate-linked moiety X motif 13Nudix motif 13PProtein KiSS-16

← Every protein Find it in the graph →

Catalysed by NUDT6 or NUDT13 or FLAD1 or NUDT12

Reaction pageLeft to rightBalanced

Rhea RHEA:48868CC BY 4.0Reference data

NADPH(4-)+waterreduced beta-nicotinamide D-ribonucleotide+adenosine 2',5'-bisphosphate+2hydron

Catalysed by NUDT13 or NUDT12

Reaction pageLeft to rightBalanced

Rhea RHEA:60820CC BY 4.0Reference data