NR0B1

Nuclear receptor that lacks a DNA-binding domain and acts as a corepressor that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency (By similarity)..

Function from UniProtKB (P51843), read 2026-09-23. CC BY 4.0.