Pathway
Membrane binding and targetting of GAG proteins
One of the mysteries of Gag protein involvement in HIV virion assembly is how the proteins are targeted to the proper membrane for budding. Infectious retroviruses do not bud from all of the available membrane surfaces within an infected cell, but primarily from the plasma membrane, which constitutes a small proportion of the total membrane surface in most cells. In polarized cells, the sites of budding are further restricted to the basolateral membrane.
REACT:R-HSA-174490Reactome
What the reference databases state
Statements
14 statements
14 statements · 1 reference database · Subject: Membrane binding and targetting of GAG proteins · Sources: Reactome
- MVB12A participates in Membrane binding and targetting of GAG proteinsProteinReactome R-HSA-174490Inferred only
- MVB12B participates in Membrane binding and targetting of GAG proteinsProteinReactome R-HSA-174490Inferred only
- NMT2 participates in Membrane binding and targetting of GAG proteinsProteinReactome R-HSA-174490Inferred only
- RPS27A participates in Membrane binding and targetting of GAG proteinsProteinReactome R-HSA-174490Inferred only
- TSG101 participates in Membrane binding and targetting of GAG proteinsProteinReactome R-HSA-174490Inferred only
- UBA52 participates in Membrane binding and targetting of GAG proteinsProteinReactome R-HSA-174490Inferred only
- UBAP1 participates in Membrane binding and targetting of GAG proteinsProteinReactome R-HSA-174490Inferred only
- UBB participates in Membrane binding and targetting of GAG proteinsProteinReactome R-HSA-174490Inferred only
- UBC participates in Membrane binding and targetting of GAG proteinsProteinReactome R-HSA-174490Inferred only
- VPS28 participates in Membrane binding and targetting of GAG proteinsProteinReactome R-HSA-174490Inferred only
- VPS37A participates in Membrane binding and targetting of GAG proteinsProteinReactome R-HSA-174490Inferred only
- VPS37B participates in Membrane binding and targetting of GAG proteinsProteinReactome R-HSA-174490Inferred only
Show the remaining 2
- VPS37C participates in Membrane binding and targetting of GAG proteinsProteinReactome R-HSA-174490Inferred only
- VPS37D participates in Membrane binding and targetting of GAG proteinsProteinReactome R-HSA-174490Inferred only