Proteins/UNIPROT:Q5BLP8

NICOL1

ProteinUNIPROT:Q5BLP8

mRNA-binding protein which interacts with a range of target mRNAs including SERPINE1, ACTA2, CCN2 and COL4A1 and may promote extracellular matrix production. Binds to the 3'-UTR of SERPINE1 mRNA and stabilizes the mRNA, possibly by competing for binding with SERBP1 and preventing SERBP1-mediated mRNA degradation. Also binds to the 3'-UTR of ACTA2. Testis-derived lumicrine factor that triggers epididymal differentiation and sperm maturation..

Function from UniProtKB (Q5BLP8), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

24 statements

24 statements · 2 reference databases · Subject: NICOL1 · Sources: Hetionet, WikiPathways

Order

NICOL1 covaries with CARMIL2ProteinHetionet hetionet:covaries:146206-401115Inferred only
NICOL1 covaries with CTCFProteinHetionet hetionet:covaries:10664-401115Inferred only
NICOL1 covaries with E2F4ProteinHetionet hetionet:covaries:1874-401115Inferred only
NICOL1 covaries with FBXO41ProteinHetionet hetionet:covaries:150726-401115Inferred only
NICOL1 covaries with GFOD2ProteinHetionet hetionet:covaries:401115-81577Inferred only
NICOL1 covaries with HOXA3ProteinHetionet hetionet:covaries:3200-401115Inferred only
NICOL1 covaries with ICMTProteinHetionet hetionet:covaries:23463-401115Inferred only
NICOL1 covaries with LEFTY2ProteinHetionet hetionet:covaries:401115-7044Inferred only
NICOL1 covaries with MESTProteinHetionet hetionet:covaries:401115-4232Inferred only
NICOL1 covaries with OIP5ProteinHetionet hetionet:covaries:11339-401115Inferred only
NICOL1 covaries with OR51I2ProteinHetionet hetionet:covaries:390064-401115Inferred only
NICOL1 covaries with PATZ1ProteinHetionet hetionet:covaries:23598-401115Inferred only

Show the remaining 12

NICOL1 covaries with PDZD8ProteinHetionet hetionet:covaries:118987-401115Inferred only
NICOL1 covaries with RRP12ProteinHetionet hetionet:covaries:23223-401115Inferred only
NICOL1 covaries with SEC11CProteinHetionet hetionet:covaries:401115-90701Inferred only
NICOL1 covaries with SEPTIN7ProteinHetionet hetionet:covaries:401115-989Inferred only
NICOL1 covaries with SERBP1ProteinHetionet hetionet:covaries:26135-401115Inferred only
NICOL1 covaries with SLC22A17ProteinHetionet hetionet:covaries:401115-51310Inferred only
NICOL1 covaries with TFE3ProteinHetionet hetionet:covaries:401115-7030Inferred only
NICOL1 covaries with TMEM160ProteinHetionet hetionet:covaries:401115-54958Inferred only
NICOL1 covaries with TMEM53ProteinHetionet hetionet:covaries:401115-79639Inferred only
NICOL1 covaries with TMEM63CProteinHetionet hetionet:covaries:401115-57156Inferred only
NICOL1 covaries with ZBTB14ProteinHetionet hetionet:covaries:401115-7541Inferred only
NICOL1 participates in 4p16 3 copy number variationPathwayWikiPathways WP5365Inferred only

Other names

3 names

Resolves to: NICOL1

Also called: C4orf48NELL2-interacting cofactor for lumicrine signalingNICOL

← Every protein Find it in the graph →