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Proteins/UNIPROT:Q13478
Within the IL18 receptor complex, responsible for the binding of the pro-inflammatory cytokine IL18, but not IL1A nor IL1B. Involved in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells. Contributes to IL18-induced cytokine production, either independently of SLC12A3, or as a complex with SLC12A3 (By similarity)..
Function from UniProtKB (Q13478), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
20 statements
20 statements · 4 reference databases · Subject: IL18R1 · Sources: gene ontology, Hetionet, Reactome, WikiPathways
1 reaction
12 names
Resolves to: IL18R1