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Proteins/UNIPROT:Q9Y295
Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP. Appears to have an intrinsic GTPase activity that is stimulated by ZC3H15/DFRP1 binding likely by increasing the affinity for the potassium ions. When hydroxylated at C-3 of 'Lys-22' by JMJD7, may bind to RNA and play a role in translation. Binds to microtubules and promotes microtubule polymerization and stability that are required for mitotic spindle assembly during prophase to anaphase transition. GTPase activity is not necessary for these microtubule-related functions..
Function from UniProtKB (Q9Y295), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
45 statements
45 statements · 4 reference databases · Subject: DRG1 · Sources: gene ontology, Hetionet, Reactome, UniProt
1 reaction
6 names
Resolves to: DRG1
Rhea RHEA:19669CC BY 4.0Reference data