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Proteins/UNIPROT:O75618
A scaffold protein that directs CASP3 to certain substrates and facilitates their ordered degradation during apoptosis. May also play a role in mediating CASP3 cleavage of KRT18. Regulates degradation of intermediate filaments during apoptosis. May play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3. Inhibits DNA transcription in vitro (By similarity)..
Function from UniProtKB (O75618), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
50 statements
50 statements · 3 reference databases · Subject: DEDD · Sources: gene ontology, Hetionet, WikiPathways
4 names
Resolves to: DEDD