Proteins/UNIPROT:Q9NUL7

DDX28

ProteinUNIPROT:Q9NUL7

Plays an essential role in facilitating the proper assembly of the mitochondrial large ribosomal subunit and its helicase activity is essential for this function. May be involved in RNA processing or transport. Has RNA and Mg(2+)-dependent ATPase activity..

Function from UniProtKB (Q9NUL7), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

12 statements

12 statements · 1 reference database · Subject: DDX28 · Sources: Hetionet

Order

DDX28 covaries with OTUD1ProteinHetionet hetionet:covaries:220213-55794Inferred only
TMEM238 covaries with DDX28ProteinHetionet hetionet:covaries:388564-55794Inferred only
CUL3 interacts with DDX28ProteinHetionet hetionet:interacts:55794-8452Inferred only
MRPL58 interacts with DDX28ProteinHetionet hetionet:interacts:3396-55794Inferred only
CAPN1 increases the expression of DDX28ProteinHetionet hetionet:regulates:823-55794Inferred only
CBR1 increases the expression of DDX28ProteinHetionet hetionet:regulates:873-55794Inferred only
HSD17B8 increases the expression of DDX28ProteinHetionet hetionet:regulates:7923-55794Inferred only
MDH2 decreases the expression of DDX28ProteinHetionet hetionet:regulates:4191-55794Inferred only
PAN2 decreases the expression of DDX28ProteinHetionet hetionet:regulates:9924-55794Inferred only
WTAP increases the expression of DDX28ProteinHetionet hetionet:regulates:9589-55794Inferred only
YTHDF2 increases the expression of DDX28ProteinHetionet hetionet:regulates:51441-55794Inferred only
ZNF143 increases the expression of DDX28ProteinHetionet hetionet:regulates:7702-55794Inferred only

Reactions

1 reaction

ATP(4-)+waterADP(3-)+hydrogenphosphate+hydron
Catalysed by HFM1 or SMCHD1 or FIGNL2 or DDX39A or DDX3X or CHD1 or CHD2 or TOR1A or TOR1B or DDX3Y or DHX15 or GET3 and 193 more alternatives

Other names

2 names

Resolves to: DDX28

Also called: MDDX28Mitochondrial DEAD box protein 28

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