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Proteins/UNIPROT:P12111

COL6A3

Protein·UNIPROT:P12111

Open in the graph

Collagen VI acts as a cell-binding protein.

Function from UniProtKB (P12111), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

GenCC submitters' classifications

7 rows

Bethlem myopathy has a germline basis in COL6A3DiseaseGenCC HGNC:2213|MONDO:0008029Inferred only
Bethlem myopathy 1A has a germline basis in COL6A3DiseaseGenCC HGNC:2213|MONDO:0024530Inferred only
collagen 6-related myopathy has a germline basis in COL6A3DiseaseGenCC HGNC:2213|MONDO:0100225Inferred only
dystonia 27 has a germline basis in COL6A3DiseaseGenCC HGNC:2213|MONDO:0014627Inferred only
Ullrich congenital muscular dystrophy has a germline basis in COL6A3DiseaseGenCC HGNC:2213|MONDO:0000355Inferred only
Ullrich congenital muscular dystrophy 1A has a germline basis in COL6A3DiseaseGenCC HGNC:2213|MONDO:0009681Inferred only
Ullrich congenital muscular dystrophy 1C has a germline basis in COL6A3DiseaseGenCC HGNC:2213|MONDO:0958236Inferred only

Statements

29 statements

29 statements · 3 reference databases · Subject: COL6A3 · Sources: Hetionet, Reactome, WikiPathways

Search this listOrder

SLC17A3 covaries with COL6A3ProteinHetionet hetionet:covaries:10786-1293Inferred only
COL6A3 covaries with SYT8ProteinHetionet hetionet:covaries:1293-90019Inferred only
COL6A3 interacts with DYSFProteinHetionet hetionet:interacts:1293-8291Inferred only
COL6A3 interacts with MMP2ProteinHetionet hetionet:interacts:1293-4313Inferred only
COL6A3 interacts with PDIA3ProteinHetionet hetionet:interacts:1293-2923Inferred only
COL6A3 participates in 2q37 copy number variation syndromePathwayWikiPathways WP5224Inferred only
COL6A3 participates in Assembly of collagen fibrils and other multimeric structuresPathwayReactome R-HSA-2022090Inferred only
COL6A3 participates in Axon guidancePathwayReactome R-HSA-422475Inferred only
COL6A3 participates in Collagen biosynthesis and modifying enzymesPathwayReactome R-HSA-1650814Inferred only
COL6A3 participates in Collagen chain trimerizationPathwayReactome R-HSA-8948216Inferred only
COL6A3 participates in Collagen degradationPathwayReactome R-HSA-1442490Inferred only
COL6A3 participates in Collagen formationPathwayReactome R-HSA-1474290Inferred only

Show the remaining 17

COL6A3 participates in Degradation of the extracellular matrixPathwayReactome R-HSA-1474228Inferred only
COL6A3 participates in Developmental BiologyPathwayReactome R-HSA-1266738Inferred only
COL6A3 participates in ECM proteoglycansPathwayReactome R-HSA-3000178Inferred only
COL6A3 participates in Extracellular matrix organizationPathwayReactome R-HSA-1474244Inferred only
COL6A3 participates in Integrin cell surface interactionsPathwayReactome R-HSA-216083Inferred only
COL6A3 participates in miRNA targets in ECM and membrane receptorsPathwayWikiPathways WP2911Inferred only
COL6A3 participates in NCAM signaling for neurite out-growthPathwayReactome R-HSA-375165Inferred only
COL6A3 participates in NCAM1 interactionsPathwayReactome R-HSA-419037Inferred only
COL6A3 participates in Nervous system developmentPathwayReactome R-HSA-9675108Inferred only
COL6A3 participates in PI3K Akt signalingPathwayWikiPathways WP4172Inferred only
COL6A3 participates in Signal TransductionPathwayReactome R-HSA-162582Inferred only
COL6A3 participates in Signaling by PDGFPathwayReactome R-HSA-186797Inferred only
COL6A3 participates in Signaling by Receptor Tyrosine KinasesPathwayReactome R-HSA-9006934Inferred only
COQ8A decreases the expression of COL6A3ProteinHetionet hetionet:regulates:56997-1293Inferred only
DHDDS decreases the expression of COL6A3ProteinHetionet hetionet:regulates:79947-1293Inferred only
SOX2 decreases the expression of COL6A3ProteinHetionet hetionet:regulates:6657-1293Inferred only
VRK3 decreases the expression of COL6A3ProteinHetionet hetionet:regulates:51231-1293Inferred only

Other names

2 names

Resolves to: COL6A3

Also called: Collagen alpha-3VI

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