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Proteins/UNIPROT:Q2KHT3
Regulator of mitophagy through the upstream regulation of the RNF41/NRDP1-PRKN pathway. Mitophagy is a selective form of autophagy necessary for mitochondrial quality control. The RNF41/NRDP1-PRKN pathway regulates autophagosome-lysosome fusion during late mitophagy. May protect RNF41/NRDP1 from proteasomal degradation, RNF41/NRDP1 which regulates proteasomal degradation of PRKN. Plays a key role in beta cells functions by regulating mitophagy/autophagy and mitochondrial health..
Function from UniProtKB (Q2KHT3), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
45 statements
45 statements · 3 reference databases · Subject: CLEC16A · Sources: gene ontology, Hetionet, WikiPathways
3 names
Resolves to: CLEC16A