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Proteins/UNIPROT:Q9HBB8
Intermicrovillar adhesion molecule that forms, via its extracellular domain, calcium-dependent heterophilic complexes with CDHR2 on adjacent microvilli. Thereby, controls the packing of microvilli at the apical membrane of epithelial cells. Through its cytoplasmic domain, interacts with microvillus cytoplasmic proteins to form the intermicrovillar adhesion complex/IMAC. This complex plays a central role in microvilli and epithelial brush border differentiation..
Function from UniProtKB (Q9HBB8), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
13 statements
13 statements · 3 reference databases · Subject: CDHR5 · Sources: gene ontology, Hetionet, WikiPathways
6 names
Resolves to: CDHR5