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A reference for what the literature reports. Not medical advice.

Proteins/UNIPROT:Q7Z4M0

REC114

Protein·UNIPROT:Q7Z4M0

Open in the graph

Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis (By similarity). Required for both spermatogenesis and oogenesis..

Function from UniProtKB (Q7Z4M0), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

GenCC submitters' classifications

1 row

oocyte maturation defect 10 has a germline basis in REC114DiseaseGenCC HGNC:25065|MONDO:0030925Inferred only

Statements

2 statements

2 statements · 1 reference database · Subject: REC114 · Sources: Hetionet

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REC114 covaries with CDHR5ProteinHetionet hetionet:covaries:283677-53841Inferred only
REC114 covaries with PPP1R15BProteinHetionet hetionet:covaries:283677-84919Inferred only

Other names

2 names

Resolves to: REC114

Also called: C15orf60Meiotic recombination protein REC114

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