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Proteins/UNIPROT:Q7Z5R6

APBB1IP

Protein·UNIPROT:Q7Z5R6

Open in the graph

Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Suppresses insulin-induced promoter activities through AP1 and SRE. Mediates Rap1-induced adhesion..

Function from UniProtKB (Q7Z5R6), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

31 statements

31 statements · 3 reference databases · Subject: APBB1IP · Sources: Hetionet, Reactome, WikiPathways

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CDHR5 covaries with APBB1IPProteinHetionet hetionet:covaries:53841-54518Inferred only
OR51A4 covaries with APBB1IPProteinHetionet hetionet:covaries:401666-54518Inferred only
EVL interacts with APBB1IPProteinHetionet hetionet:interacts:51466-54518Inferred only
HRAS interacts with APBB1IPProteinHetionet hetionet:interacts:3265-54518Inferred only
LCP2 interacts with APBB1IPProteinHetionet hetionet:interacts:3937-54518Inferred only
PFN1 interacts with APBB1IPProteinHetionet hetionet:interacts:5216-54518Inferred only
RAP1A interacts with APBB1IPProteinHetionet hetionet:interacts:54518-5906Inferred only
UBC interacts with APBB1IPProteinHetionet hetionet:interacts:54518-7316Inferred only
VASP interacts with APBB1IPProteinHetionet hetionet:interacts:54518-7408Inferred only
APBB1IP participates in DiseasePathwayReactome R-HSA-1643685Inferred only
APBB1IP participates in Diseases of signal transduction by growth factor receptors and second messengersPathwayReactome R-HSA-5663202Inferred only
APBB1IP participates in GRB2:SOS provides linkage to MAPK signaling for IntegrinsPathwayReactome R-HSA-354194Inferred only

Show the remaining 19

APBB1IP participates in HemostasisPathwayReactome R-HSA-109582Inferred only
APBB1IP participates in Integrin signalingPathwayReactome R-HSA-354192Inferred only
APBB1IP participates in MAP2K and MAPK activationPathwayReactome R-HSA-5674135Inferred only
APBB1IP participates in MAPK family signaling cascadesPathwayReactome R-HSA-5683057Inferred only
APBB1IP participates in MAPK1/MAPK3 signalingPathwayReactome R-HSA-5684996Inferred only
APBB1IP participates in Oncogenic MAPK signalingPathwayReactome R-HSA-6802957Inferred only
APBB1IP participates in p130Cas linkage to MAPK signaling for integrinsPathwayReactome R-HSA-372708Inferred only
APBB1IP participates in Paradoxical activation of RAF signaling by kinase inactive BRAFPathwayReactome R-HSA-6802955Inferred only
APBB1IP participates in Platelet activation, signaling and aggregationPathwayReactome R-HSA-76002Inferred only
APBB1IP participates in Platelet Aggregation (Plug Formation)PathwayReactome R-HSA-76009Inferred only
APBB1IP participates in RAF/MAP kinase cascadePathwayReactome R-HSA-5673001Inferred only
APBB1IP participates in Signal TransductionPathwayReactome R-HSA-162582Inferred only
APBB1IP participates in Signaling by BRAF and RAF1 fusionsPathwayReactome R-HSA-6802952Inferred only
APBB1IP participates in Signaling by high-kinase activity BRAF mutantsPathwayReactome R-HSA-6802948Inferred only
APBB1IP participates in Signaling by moderate kinase activity BRAF mutantsPathwayReactome R-HSA-6802946Inferred only
APBB1IP participates in Signaling by RAF1 mutantsPathwayReactome R-HSA-9656223Inferred only
APBB1IP participates in Signaling by RAS mutantsPathwayReactome R-HSA-6802949Inferred only
APBB1IP participates in Signaling downstream of RAS mutantsPathwayReactome R-HSA-9649948Inferred only
APBB1IP participates in TYROBP causal network in microgliaPathwayWikiPathways WP3945Inferred only

Other names

10 names

Resolves to: APBB1IP

Also called: APBB1-interacting protein 1PREL-1PREL1Proline-rich EVH1 ligand 1Proline-rich protein 73Rap1-GTP-interacting adapter moleculeRARP-1RARP1Retinoic acid-responsive proline-rich protein 1RIAM

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