Proteins/UNIPROT:Q6ZP82

CCDC141

ProteinUNIPROT:Q6ZP82

Plays a critical role in cortical radial and GnRH neurons migration during brain development. Regulates cortical radial migration by negatively controlling the activity of histone deacetylase 6 (HDAC6) and promotes centrosome maturation. CAMDI is required for dilation formation of cortical neurons during radial migration. Plays a critical role in learning and memory performance through regulation of AMPA-selective glutamate receptors (AMPARs) cell surface expression in competition with KIBRA..

Function from UniProtKB (Q6ZP82), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

1 row

Kallmann syndrome has a germline basis in CCDC141DiseaseGenCC HGNC:26821|MONDO:0018800Inferred only

Statements

23 statements

23 statements · 3 reference databases · Subject: CCDC141 · Sources: gene ontology, Hetionet, WikiPathways

Order

ARHGEF28 covaries with CCDC141ProteinHetionet hetionet:covaries:285025-64283Inferred only
CCDC141 covaries with ARL6IP4ProteinHetionet hetionet:covaries:285025-51329Inferred only
CEP295 covaries with CCDC141ProteinHetionet hetionet:covaries:285025-85459Inferred only
CCDC141 covaries with EFCAB13ProteinHetionet hetionet:covaries:124989-285025Inferred only
GSDMB covaries with CCDC141ProteinHetionet hetionet:covaries:285025-55876Inferred only
GTF3C6 covaries with CCDC141ProteinHetionet hetionet:covaries:112495-285025Inferred only
HPS4 covaries with CCDC141ProteinHetionet hetionet:covaries:285025-89781Inferred only
LCE3A covaries with CCDC141ProteinHetionet hetionet:covaries:285025-353142Inferred only
MYL5 covaries with CCDC141ProteinHetionet hetionet:covaries:285025-4636Inferred only
CCDC141 covaries with NLRP14ProteinHetionet hetionet:covaries:285025-338323Inferred only
PRR14L covaries with CCDC141ProteinHetionet hetionet:covaries:253143-285025Inferred only
CCDC141 covaries with PYDC1ProteinHetionet hetionet:covaries:260434-285025Inferred only

Show the remaining 11

STARD9 covaries with CCDC141ProteinHetionet hetionet:covaries:285025-57519Inferred only
CCDC141 covaries with THUMPD2ProteinHetionet hetionet:covaries:285025-80745Inferred only
TMTC1 covaries with CCDC141ProteinHetionet hetionet:covaries:285025-83857Inferred only
ZCCHC18 covaries with CCDC141ProteinHetionet hetionet:covaries:285025-644353Inferred only
ZNF239 covaries with CCDC141ProteinHetionet hetionet:covaries:285025-8187Inferred only
CCDC141 covaries with ZNF500ProteinHetionet hetionet:covaries:26048-285025Inferred only
CCDC141 covaries with ZSCAN29ProteinHetionet hetionet:covaries:146050-285025Inferred only
DISC1 interacts with CCDC141ProteinHetionet hetionet:interacts:27185-285025Inferred only
UBC interacts with CCDC141ProteinHetionet hetionet:interacts:285025-7316Inferred only
CCDC141 participates in HDAC6 interactions in the central nervous systemPathwayWikiPathways WP5426Inferred only
CCDC141 regulates regulation of synapse assemblyBiological processgene ontology Q6ZP82|GO:0051963Inferred only

Other names

3 names

Resolves to: CCDC141

Also called: CAMDICoiled-coil domain-containing protein 141Coiled-coil protein associated with myosin II and DISC1

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