Proteins/UNIPROT:Q9NQW6

ANLN

ProteinUNIPROT:Q9NQW6

Required for cytokinesis. Essential for the structural integrity of the cleavage furrow and for completion of cleavage furrow ingression. Plays a role in bleb assembly during metaphase and anaphase of mitosis. May play a significant role in podocyte cell migration..

Function from UniProtKB (Q9NQW6), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

2 rows

familial idiopathic steroid-resistant nephrotic syndrome has a germline basis in ANLNDiseaseGenCC HGNC:14082|MONDO:0019006Inferred only
focal segmental glomerulosclerosis 8 has a germline basis in ANLNDiseaseGenCC HGNC:14082|MONDO:0014462Inferred only

Statements

21 statements

21 statements · 4 reference databases · Subject: ANLN · Sources: gene ontology, Hetionet, Reactome, WikiPathways

Order

ANLN covaries with AS3MTProteinHetionet hetionet:covaries:54443-57412Inferred only
OR2T1 covaries with ANLNProteinHetionet hetionet:covaries:26696-54443Inferred only
OR2T8 covaries with ANLNProteinHetionet hetionet:covaries:343172-54443Inferred only
STK17A covaries with ANLNProteinHetionet hetionet:covaries:54443-9263Inferred only
ANLN covaries with ZNF554ProteinHetionet hetionet:covaries:115196-54443Inferred only
ANLN covaries with ZNF584ProteinHetionet hetionet:covaries:201514-54443Inferred only
SEPTIN7 interacts with ANLNProteinHetionet hetionet:interacts:54443-989Inferred only
SUMO1 interacts with ANLNProteinHetionet hetionet:interacts:54443-7341Inferred only
UBC interacts with ANLNProteinHetionet hetionet:interacts:54443-7316Inferred only
ANLN participates in Nephrotic syndromePathwayWikiPathways WP4758Inferred only
ANLN participates in PtdIns 4 5 P2 in cytokinesis pathwayPathwayWikiPathways WP5199Inferred only
ANLN participates in Retinoblastoma gene in cancerPathwayWikiPathways WP2446Inferred only

Show the remaining 9

ANLN participates in RHO GTPase cyclePathwayReactome R-HSA-9012999Inferred only
ANLN participates in RHOA GTPase cyclePathwayReactome R-HSA-8980692Inferred only
ANLN participates in RHOB GTPase cyclePathwayReactome R-HSA-9013026Inferred only
ANLN participates in RHOC GTPase cyclePathwayReactome R-HSA-9013106Inferred only
ANLN participates in Signal TransductionPathwayReactome R-HSA-162582Inferred only
ANLN participates in Signaling by Rho GTPasesPathwayReactome R-HSA-194315Inferred only
ANLN participates in Signaling by Rho GTPases, Miro GTPases and RHOBTB3PathwayReactome R-HSA-9716542Inferred only
ANLN regulates positive regulation of bleb assemblyBiological processgene ontology Q9NQW6|GO:1904172Inferred only
ANLN regulates regulation of exit from mitosisBiological processgene ontology Q9NQW6|GO:0007096Inferred only

Other names

1 name

Resolves to: ANLN

Also called: Anillin

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