ADGRG4

Orphan adhesion G protein-coupled receptor (aGPCR) (By similarity). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase (By similarity). ADGRG4 is coupled to G(s) G proteins and mediates activation of adenylate cyclase activity. May be act as sensor of mechanical forces..

Function from UniProtKB (Q8IZF6), read 2026-09-23. CC BY 4.0.