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Proteins/UNIPROT:Q5H8C1

FREM1

Protein·UNIPROT:Q5H8C1

Open in the graph

Extracellular matrix protein that plays a role in epidermal differentiation and is required for epidermal adhesion during embryonic development..

Function from UniProtKB (Q5H8C1), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

GenCC submitters' classifications

5 rows

BNAR syndrome has a germline basis in FREM1DiseaseGenCC HGNC:23399|MONDO:0012165Inferred only
isolated trigonocephaly has a germline basis in FREM1DiseaseGenCC HGNC:23399|MONDO:0018065Inferred only
oculotrichoanal syndrome has a germline basis in FREM1DiseaseGenCC HGNC:23399|MONDO:0009560Inferred only
renal agenesis, unilateral has a germline basis in FREM1DiseaseGenCC HGNC:23399|MONDO:0019636Inferred only
trigonocephaly 2 has a germline basis in FREM1DiseaseGenCC HGNC:23399|MONDO:0013774Inferred only

Statements

4 statements

4 statements · 2 reference databases · Subject: FREM1 · Sources: Hetionet, WikiPathways

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ADGRG4 covaries with FREM1ProteinHetionet hetionet:covaries:139378-158326Inferred only
LAMB4 covaries with FREM1ProteinHetionet hetionet:covaries:158326-22798Inferred only
LCE3A covaries with FREM1ProteinHetionet hetionet:covaries:158326-353142Inferred only
FREM1 participates in Development of ureteric derived collecting systemPathwayWikiPathways WP5053Inferred only

Other names

6 names

Resolves to: FREM1

Also called: C9orf143C9orf145C9orf154FRAS1-related extracellular matrix protein 1Protein QBRICKQBRICK

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